Results 81 to 90 of about 22,485 (236)

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

Immunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Building the foundations for an international patient‐centred outcomes set for psoriasis: A scoping study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This scoping study refined the first patient‐centred outcome set for psoriasis, involving patient representatives and dermatologists from 22 countries. The proposal includes 18 patient‐relevant outcomes, 2 patient experiences, corresponding outcome measurement instruments and 50 case‐mix variables.
Emma Vyvey, Rani Soenen, Hazel H. Oon, Sicily Mburu, Maren Awici‐Rasmussen, Azura Mohd Affandi, Wayne Gulliver, Siew Eng Choon, Tiago Torres, Allison FitzGerald, Alvaro Gonzalez‐Cantero, Anna López‐Ferrer, Chih‐Hung Lee, Fernando Valenzuela, Julia‐Tatjana Maul, Luis Puig, Masanori Okuse, Mohamed EL‐Komy, Peter Foley, Ron Vender, Wolf‐Henning Boehncke, Josef Pohunek, Ya Hsin Wang, Angela Londoño‐García, Gail Todd, Margarita Velasquez‐Lopera, Mark Lebwohl, Edmund Lau, Marcus Schmitt‐Egenolf, Niels Hilhorst, Spencer Connell, Elfie Deprez, Nanja van Geel, Christopher Griffiths, Peter Van de Kerkhof, Jo Lambert   +35 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

An Analysis of the clinical and investigative profile of uveitis in the elderly: First case series from India

Indian Journal of Ophthalmology
Purpose: To evaluate the spectrum of uveitis occurring after 60 years of age in elderly patients who presented to a tertiary care eye center in India. Methods: Retrospective study of patients who visited a tertiary eye care institute between January 2010
Kowsigan Magesan, Arshee Ahmed, Amala E George, Sudha K Ganesh, Jyotirmay Biswas, Parthopratim Dutta Majumder   +5 more
doaj   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

Transplant Infectious Disease, EarlyView.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni, Andrea Cona, Malgorzata Mikulska, Francesca Pecoraro, Carlotta Piazza, Elda De Vita, Giada Pietrosi, Matteo Bulati, Tiziana Lazzarotto, Mario Luppi   +9 more
wiley   +1 more source

Pattern of uveitis in North East India: A tertiary eye care center study

Indian Journal of Ophthalmology, 2009
We conducted an institutional-based retrospective study on 308 uveitic patients and analyzed the pattern of uveitis in Northeastern India. Anterior uveitis was the most common type (47.07%) followed by posterior (29.87%), intermediate (12 ...
Das Dipankar, Bhattacharjee Harsha, Bhattacharyya Pankaj, Jain Lokesh, Panicker M, Das Kalyan, Deka Akshay   +6 more
doaj  

Epidemiology of Uveitis from a Tertiary Referral Hospital in Bulgaria over a 13-Year Period

Diagnostics
Objectives: The aim of this study was to establish the etiology of uveitis and to examine its relationship with anatomical localization, age, and gender.
Vesela Todorova Mitkova-Hristova, Marin Anguelov Atanassov, Yordanka Mincheva Basheva-Kraeva, Velichka Zaharieva Popova, Krasimir Iliev Kraev, Steffanie Hristova Hristova   +5 more
doaj   +1 more source

Prevalence and outcome of lens capsule disruption in routine canine cataract surgery: A retrospective study of 520 eyes (2012–2019)

Veterinary Ophthalmology, Volume 28, Issue 2, Page 141-149, March 2025.
Abstract Objective To investigate the prevalence and surgical outcome of lens capsule disruption (LCD) in dogs undergoing cataract removal. Animals studied Medical records of 924 eyes undergoing phacoemulsification were analyzed retrospectively. Procedures Routine cataract surgeries with or without LCD were included. Any LCD other than routine anterior
Amy L. M. M. Andrews, Christiane Kafarnik, Maria‐Christine Fischer   +2 more
wiley   +1 more source

Demography in Swiss paediatric uveitis: a retrospective cohort study

Journal of Ophthalmic Inflammation and Infection
Introduction Paediatric uveitis is a rare disease. It can affect any segment and have various etiologies, including infectious, autoimmune, and masquerade diseases.
Jeanne Martine Gunzinger, Alice Kitay, Fabio Meier, Christian Böni, Seraina Palmer Sarott, Brigitte Simonsz-Tóth, Christina Gerth-Kahlert   +6 more
doaj   +1 more source

Evaluation for endotoxin in intraocular materials used during phacoemulsification surgery using a recombinant factor C assay

Veterinary Ophthalmology, Volume 28, Issue 2, Page 481-485, March 2025.
Abstract Objective Cataract surgery remains the sole method to resolve blindness secondary to cataract formation. One complication includes fibrin web formation post‐operatively. This study aimed to investigate the presence of endotoxin within materials used during cataract surgery as a possible cause of fibrin web phenomenon. Methods Preservative‐free
Taylor A. Opgenorth, Eryn L. Opgenorth, J. Seth Eaton, Ellison Bentley   +3 more
wiley   +1 more source