Results 191 to 200 of about 78,339 (310)

Beyond the Kidney and Lung: Cutaneous and Mucosal Clues to Human Hantavirus Disease

International Journal of Dermatology, Volume 65, Issue 10, Page 2018-2027, October 2026.
Rodent exposure and aerosolized excreta can lead to hantavirus infection with systemic endothelial injury and capillary leak, resulting in thrombocytopenia and syndromes such as HPS/HCPS and HFRS/NE. Early dermatologic and mucosal findings, including flushing, conjunctival injection, petechiae/purpura, and mucosal bleeding, may provide important clues ...
Giuseppe Gallo, Pietro Quaglino, Simone Ribero   +2 more
wiley   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, Volume 78, Issue 9, Page 1195-1200, September 2026.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Exploring the Involvement of <i>ERAP1</i> in the Pathogenesis of Non-Infectious Uveitis: A Systematic Review. [PDF]

Life (Basel)
Rizea IM, Stanca HT, Potop V, Dăscălescu DM, Andrei SI, Tofolean IT, Popa-Cherecheanu A, Munteanu M, Cherciu M, Popa OM.   +9 more
europepmc   +1 more source

Reduction of CXCR3+CCR6+ CD4+ T Cells and IL‐17+ RORγt+ CD4+ T Cells During Secukinumab Treatment Identifies Patients With Axial Spondyloarthritis Responsive to Subsequent Biologic Therapy

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective We recently reported an immune profile that stratifies patients with axial spondyloarthritis based on clinical response to secukinumab. We now undertake an exploratory study on the secukinumab nonresponder patients to determine if immunologic changes occur during their initial secukinumab treatment that could determine their next biologic ...
Addison Pacheco, Patricia Remalante‐Rayco, Nigil Haroon, Denis Poddubnyy, Robert D. Inman   +4 more
wiley   +1 more source

Spondyloarthritis Research and Treatment Network Recommendations for the Referral of Adults With Chronic Back Pain and Suspected Axial Spondyloarthritis to a Rheumatologist

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective In the United States, axial spondyloarthritis (axSpA) diagnosis is delayed up to 14 years preventing effective management. We convened a multidisciplinary clinician and patient group to develop recommendations for rheumatology referral of adults with chronic back pain.
Maureen Dubreuil, Abhijeet Danve, Jean W. Liew, Swetha Ann Alexander, Yuliya Afinogenova, Mohamad Bittar, Liana Fraenkel, Alyssa Grimshaw, Anand Kumthekar, Michael P. LaValley, Marina Nighat Magrey, Vikas Majithia, Sali Merjanah, Hillary Norton, Jessica A Walsh, Atul Deodhar   +15 more
wiley   +1 more source

Pars plana vitrectomy in uveitis of diverse etiologies: indications and surgical outcomes. [PDF]

BMC Ophthalmol
Zorlutuna Kaymak N, Kanar HS, Akcay G, Kılınç ET, Sungu I, Oklar M, Tanyıldız B.   +6 more
europepmc   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1989-1999, September 2026.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini, Marianna Lucafò, Debora Curci, Davide Selvestrel, Valentina Moressa, Sofia Pagarin, Barbara Bellich, Martina Franzin, Alberto Tommasini, Mara L. Becker, Laura B. Ramsey, Susan D. Thompson, Carl D. Langefeld, Federica Corba, Edoardo Marrani, Gabriele Simonini, Gabriele Stocco, Giuliana Decorti, Andrea Taddio, Serena Pastore   +19 more
wiley   +1 more source

Tissue Damage in Rheumatoid Arthritis Is Genetically Linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1837-1849, September 2026.
Objective Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biologic mechanism underlying this association. Methods Expression of surrounding genes was compared among rs26232 genotypes.
Kevin J. Sheridan, Emma R. Dorris, Maria Inês Pimenta, Jemma Falkov, Matthew Fisher, Sam Pledger, Hector Devey, Munitta Muthana, Denis C. Shields, Richard E. Mains, Betty A. Eipper, Christopher D. Buckley, Anthony G. Wilson   +12 more
wiley   +1 more source

Association between immune checkpoint inhibitors and the risk and prognosis of uveitis: a meta-analysis. [PDF]

Front Immunol
Li Q, Mei Y, Liu Y, Li X, Wang Y, Zhou C, Mou W.   +6 more
europepmc   +1 more source

Beyond the Rash: Simultaneous Bilateral Facial Nerve Palsy Following Childhood Varicella Infection

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Bilateral facial nerve palsy is a rare neurological condition in children and is infrequently associated with primary Varicella (chickenpox) infection. We report the case of a 10‐year‐old previously healthy girl who developed simultaneous bilateral lower motor neuron facial weakness 3 weeks after a self‐limiting varicella infection.
Mohamed Sheikh Hassan, Abdiwahid Ahmed Ibrahim, Said Abdi Mohamed, Nor Osman Sidow, Said Abdirahman Ahmed, Nur Adam Mohamed, Mohamed Mukhtar Mohamed, Saadaq Adan Hussein   +7 more
wiley   +1 more source