Results 31 to 40 of about 4,988 (227)

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Avaliação tomográfica do posicionamento de parafusos pediculares em deformidades na coluna torácica e lombar introduzidos com base na técnica "free hand" Evaluación tomográfica de la colocación de tornillos pediculares en deformidades de la columna torácica y lumbar, introducidos con base en la técnica "free hand" Tomographic evaluation of the placement of pedicle screws used in deformities of the thoracic and lumbar spine based on the "free hand" technique

Coluna/Columna, 2011
OBJETIVO: Avaliar o posicionamento de parafusos pediculares aplicados em vértebras da coluna torácica e lombar em pacientes portadores de escolioses, introduzidos pela técnica "free hand".
Dante Bernardes Giubilei, Paulo Tadeu Maia Cavali, Maurício Antonelli Lehoczki, Alexander Junqueira Rossato, Marcelo Italo Risso-Neto, Guilherme Rebechi Zuiani, Ivan Guidolin Veiga, Wagner Pasqualini, Élcio Landim   +8 more
doaj   +1 more source

¿Existe simetría en la artrosis vertebral? [PDF]

, 2011
X Congreso Nacional de Paleopatología.
Campo Martín, Manuel, Coscollano Pérez, H., González Martín, A.   +2 more
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Neurocitoma retroperitoneal con crecimiento intrarraquídeo

Cirugía del Uruguay, 1979
Los autores presentan un caso de neurocitos ma (ganglioneuroma) retroperitoneal con invasión del canal raquídeo a través. de los agujeros de conjugación de las vértebras lumbares L2 y L3, resecado en tres actos operatorios sucesivos mediante abordaje tra,
Pedro Benedek, Francisco Crestanello, Esteban Nin Vivo, Juan Purriel, Miguel Estable, Bartolomé Grillo   +5 more
doaj  

Conocimientos anatómicos en las diferentes técnicas de masajes en la columna vertebral [PDF]

, 2013
El propósito del desarrollo temático de ésta ponencia es, conocer la importancia de los masajes sobre el aparato articular y locomotor, en este caso sobre la musculatura del dorso más especificamente en los músculos antigravitatorios o extensores de la ...
Manrique, Laura
core   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

Damage control in thoracic and lumbar unstable fractures in polytrauma. Systematic review

Coluna/Columna, 2015
The objective of this systematic review was to integrate the information from existing studies to determine the level of evidence and grade of recommendation of the implementation of damage control in unstable thoracic and lumbar fractures in ...
Javier Peña Chávez, José Manuel Pérez Atanasio, Edgar Abel Márquez García, Juan Carlos de la Fuente Zuno, Rubén Torres González   +4 more
doaj   +1 more source

¨FACTORES ASOCIADOS A LA FRECUENCIA DE LUMBALGIA EN CONDUCTORES DE TAXI CON BASE EN EL METRO CUATRO CAMINOS, MUNICIPIO DE NAUCALPAN ESTADO DE MÉXICO EN EL AÑO 2012¨ [PDF]

, 2013
La función del fisioterapeuta va más allá del tratamiento de personas con algún tipo de lesión o problema, el papel de un terapeuta físico empieza con la prevención, tanto aconsejando y transmitiendo sus conocimientos para evitar lesiones.
Albiter Hernández, Flor, López Díaz, Héctor Urbano   +1 more
core  

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source