Results 171 to 180 of about 358,140 (209)

Neuroinflammatory and Motor Alterations in LRRK2*G2019S Transgenic Mice Without Enhanced Vulnerability to Aging or Chronic MPTP‐Induced Nigrostriatal Neurodegeneration

open access: yesJournal of Neurochemistry, Volume 170, Issue 9, September 2026.
LRRK2 G2019S mutation is the most common genetic cause of Parkinson's disease but its contribution to nigrostriatal neurodegeneration, particularly in response to mitochondrial dysfunction, remains unclear. hLRRK2*G2019S transgenic mice exhibited early microglial activation and motor alterations, but not increased dopaminergic nigrostriatal ...
Roberto García‐Swinburn   +8 more
wiley   +1 more source

Self‐Care Behaviors in Osteoporosis: A Cross‐Cultural Study Using Multidimensional Analysis of Textual Data

open access: yesJournal of Nursing Scholarship, Volume 58, Issue 5, September 2026.
ABSTRACT Introduction Osteoporosis is a chronic skeletal condition that significantly affects daily life and may benefit from adequate self‐care. The Middle‐Range Theory of Self‐Care of Chronic Illness conceptualizes self‐care as a naturalistic process encompassing maintenance, monitoring, and management, also shaped by contextual and cultural factors.
Chiara Tedesco   +14 more
wiley   +1 more source

Unilateral Chewing Frequency and Self‐Reported Mastication Satisfaction: A Cross‐Sectional Study

open access: yesJournal of Oral Rehabilitation, Volume 53, Issue 9, Page 1601-1607, September 2026.
Frequent unilateral chewing is associated with reduced self‐reported mastication satisfaction. The lowest satisfaction was reported among individuals engaging in constant unilateral chewing, independent of demographic and psychological factors. ABSTRACT Objective This study aimed to assess the association between unilateral chewing frequency and self ...
Carlo Ciotola   +3 more
wiley   +1 more source

ENLIGHTENme: Translating the Benefits of Self‐Administered Daytime Light Supplementation to Older Adults in the Real World

open access: yesJournal of Pineal Research, Volume 78, Issue 5, September 2026.
ABSTRACT Controlled studies have demonstrated that light supplementation benefits circadian entrainment, sleep and mood. Translating these findings into effective, real‐world usage of light supplementation is, however, challenging because naturalistic and supplemental light exposure are shaped by personal habits and environmental light conditions ...
Débora B. Constantino   +18 more
wiley   +1 more source

Danon Disease: Understanding the Role of LAMP2 Variants in Cardiomyopathy and Multisystemic Involvement. [PDF]

open access: yesArq Bras Cardiol
Ribeiro GNP   +7 more
europepmc   +1 more source

Real‐World Effectiveness and Safety of iGlarLixi in People With Type 2 Diabetes in LATAM Region: A Subanalysis of the SUCCESS Study

open access: yes
Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8724-8728, September 2026.
Juan Manuel Arteaga‐Diaz   +4 more
wiley   +1 more source

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz   +17 more
wiley   +1 more source

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