Results 231 to 240 of about 1,989,476 (247)

Cucurbit Leaf Crumple Virus: An Important Pathogen of Cucurbit and Snap Bean Crops. [PDF]

Mol Plant Pathol
Dhadly DK, Kavalappara SR, Bag S, McAvoy T, Severns PM, Srinivasan R, Simmons AM.   +6 more
europepmc   +1 more source

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

Advanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina, Adam Tam, Jennifer Lam, Nila C. Wu, Nancy T. Li, Alison P. McGuigan   +5 more
wiley   +1 more source

New Insights Into an Old Vaccine: Potency and Breadth of Neutralizing Antibodies Elicited by Yellow Fever Vaccine 17D Are Boosted by Heterologous Orthoflavivirus Infection. [PDF]

J Infect Dis
Coulter FJ, Micheletti CA, Estrada AE, Luo S, Osman SR, Nix CD, Hu SY, Sampouw SM, Kareko BW, Naleway AL, Messer WB.   +10 more
europepmc   +1 more source

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

Advanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino, Phuoc Thien Phan, James Davies, Bibhu Sharma, Tianruo Guo, Chi Cong Nguyen, Nigel H. Lovell, Thanh Nho Do   +7 more
wiley   +1 more source

Molecular Insights into High-Pathogenicity RNA Viruses. [PDF]

Viruses
Krnjić H, Hrapović A, Galijatović A, Tipura A, Hajdarpašić M, Kozarić S, Berilo A, Odobašić N, Hromić-Jahjefendić A, Šutković J.   +9 more
europepmc   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Molecular characterization of a novel partitivirus harboring an additional third dsRNA segment from Trichoderma harzianum. [PDF]

Arch Virol
Kim JE, Chun J, Ko YH, Kim DH.
europepmc   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Cameroonian ticks, uncharted viromes: new insights from Rhipicephalus microplus. [PDF]

Virus Res
Govaerts K, Vanmechelen B, Ysebaert L, De Coninck L, Horemans M, Ebwanga EJ, Ghogomu SM, Paeshuyse J, Matthijnssens J, Baele G.   +9 more
europepmc   +1 more source