Results 121 to 130 of about 7,391,818 (293)

Some expressions for the strain energy in a finite volume surrounding the root of blunt V-notches

, 2005
The paper gives some closed form expressions for the strain energy averaged in a finite size volume surrounding the root of blunt V-shaped notches under Mode I loading. The control volume, reminiscent of Neuber's concept of elementary structural volumes,
LAZZARIN, PAOLO, Lazzarin P., BERTO, FILIPPO, Berto F.   +3 more
core   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Stress concentration at notches

, 2017
This book compiles solutions of linear theory of elasticity problems for isotropic and anisotropic bodies with sharp and rounded notches. It contains an overview of established and recent achievements, and presents the authors’ original solutions in the ...
Kazberuk, Andrzej, Savruk, Mykhaylo P
core   +1 more source

Study on notch tensile properties of Fe-Mn-Si shape memory alloy

Materials Research Express
In order to investigate the effect of stress concentration on the mechanical properties of Fe-Mn-Si shape memory alloy, Fe17Mn5Si10Cr5Ni shape memory alloy was selected as the research object in this study.
Haojie Niu, Yubin Sun, Chengxin Lin
doaj   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Stress concentration near sharp and rounded V-shaped notches

, 2013
Наведено огляд досліджень концентрації напружень у пружних тілах, послаблених гострими та закругленими кутовими вирізами. Особливу увагу приділено єдиному підходу до вивчення розподілу напружень біля таких концентраторів напружень, коли коефіцієнти ...
Панасюк, В.В., Казберук, А., Саврук, М.П.   +2 more
core  

Averaged strain energy density and J-integral for U- and blunt V-shaped notches under torsion

, 2014
Analytical solutions for the J-integral and the strain energy density (SED) averaged over a control volume are presented for U- and blunt V-shaped notches under torsion. The influence of the notch tip radius and the notch opening angle are fully included
LAZZARIN, PAOLO, ZAPPALORTO, MICHELE, BERTO, FILIPPO   +2 more
core   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Brittle Fracture of Rounded V-Notches in Isostatic Graphite under Static Multiaxial Loading

, 2015
While a large bulk of experimental results from cracked specimens of polycrystalline graphite under pure modes of loading, in particular under mode I loading, can be found in the literature, only a very limited number of tests have been carried out on ...
CAMPAGNOLO, ALBERTO, Ayatollahi, M. R., BERTO, FILIPPO   +2 more
core   +1 more source