Results 231 to 240 of about 443,126 (283)

Plaque-associated microglial polarization in visual brain regions of the 5xFAD mouse model. [PDF]

Front Aging Neurosci
McCool S, Jain A, Smith JC, Van Hook MJ.
europepmc   +1 more source

Entdeckung eines antiviralen Elektronentransferprozesses zur Erzeugung katalytisch selbstversorgender viraler Restriktionsfaktoren

Angewandte Chemie, EarlyView.
CYB5R3 wird als mutmaßlicher Elektronentransferpartner von Viperin (RSAD2) identifiziert, was erklärt, warum die ER‐Lokalisation für die antivirale Aktivität erforderlich ist. Dieses Wissen ermöglichte die Entwicklung immunstiller, katalytisch selbstversorgender antiviraler Restriktionsfaktor‐Enzyme (iCAREs), die ein antivirales Nukleosidtriphosphat ...
Mengdi Wu, Nghi Thao Hoang, Deborah Grifagni, Meritxell Wu‐Lu, Yujie Sheng, Theo Situmorang, Pei‐Hsin Tai, Zheng Chen, Astrid Maluta, Mohammed Hakil, Bianca Susini, Hannah Florance, Peter‐Leon Hagedoorn, John Mark Sutton, Maria‐Andrea Mroginski, Simone Ciofi‐Baffoni, Kourosh H. Ebrahimi   +16 more
wiley   +1 more source

Alternative splicing in layer 3 pyramidal neurons differs across regions of the human cortical hierarchy. [PDF]

Cereb Cortex
Dowling KF, Enwright Iii JF, Arion D, Lewis DA.   +3 more
europepmc   +1 more source

3D Liquid Crystal Framework Enclosing Dual Compartments

Angewandte Chemie, EarlyView.
A new type of liquid crystal phase is reported, having the conjugated rod‐like molecular cores form a 3D framework of elongated octahedral cages filled alternatively with alkyl and fluoroalkyl pendant chains. The cages are held together by flexible H‐bonding hinges, making them adaptable to thermal expansion and stable in a wide temperature range.
Yang‐yang Zhao, Huan‐jun Lu, Helgard Ebert, Xiang‐bing Zeng, Chunlan Ma, Feng Liu, Carsten Tschierske, Goran Ungar   +7 more
wiley   +2 more sources

Neurophysiological basis for visual distortions in amblyopia. [PDF]

Front Neurosci
Goulet L, Farivar R.
europepmc   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, EarlyView.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

Docosahexaenoic Acid (DHA) Deficiency in Breast Milk: A Cross-Sectional Study of Lactating Women in Serbia, Montenegro, and North Macedonia. [PDF]

Nutrients
Niseteo T, Ilić A, Cupara N, Đurović D, Dimitrovska M, Poček L, Pop Lazarova M, Martić J.   +7 more
europepmc   +1 more source

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

Angewandte Chemie, EarlyView.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia, Giusy Carleo, Zhenni Yang, Francesca Di Matteo, Federica De Rosa, Gerardina Smaldone, Zhao‐Bing Gao, Marco D'Alì, Rita Turcio, Demin Ma, Veronica Di Sarno, Nannan Su, Salvatore Vincenzo Giofrè, Giacomo Pepe, Pietro Campiglia, Alessia Bertamino, Francesco Miceli, Jiangtao Guo, Nunzio Iraci, Carmine Ostacolo, Maurizio Taglialatela   +20 more
wiley   +2 more sources

Short-term efficacy and safety of 5MHz fractional microneedle radiofrequency for facial rejuvenation: a prospective study. [PDF]

Ann Med
Qiu H, Wu X, Wu Y, Xu J, Zhu Y, Chen J, Chen X, Zhong P, Wang F, Lin Q, Li F, Xu T.   +11 more
europepmc   +1 more source