Results 171 to 180 of about 3,473 (240)

The Society for Translational Medicine: clinical practice guidelines for the postoperative management of chest tube for patients undergoing lobectomy. [PDF]

open access: yesJ Thorac Dis, 2017
Gao S   +92 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens. [PDF]

open access: yesProc Natl Acad Sci U S A, 2013
Cywes-Bentley C   +21 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Sketching AI Concepts with Capabilities and Examples: AI Innovation in the Intensive Care Unit. [PDF]

open access: yesProc SIGCHI Conf Hum Factor Comput Syst
Yildirim N   +16 more
europepmc   +1 more source

Uniportal video-assisted thoracoscopic bronchoplastic and carinal sleeve procedures. [PDF]

open access: yesJ Thorac Dis, 2016
Gonzalez-Rivas D   +7 more
europepmc   +1 more source

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