Results 51 to 60 of about 105,594 (305)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Vacancy-Regulated Charge Carrier Dynamics and Suppressed Nonradiative Recombination in Two-Dimensional ReX₂ (X = S, Se)

, 2022
Point defects in semiconductors usually act as nonradiative charge carrier recombination centers, which severely limit the performance of optoelectronic devices. In this work, by combining time-domain density functional theory with nonadiabatic molecular
Chenqiang Hua (5953427), Wenzhen Dou (10046903), Biyu Song (10285247), Miao Zhou (1440016), Meimei Wu (1756879), Ling Zhang (18071), Tianchao Niu (1683400)   +6 more
core   +2 more sources

CURRENT TRENDS OF ATTRACTING YOUNG PROFESSIONALS TO ORGANIZATIONS

Вестник университета, 2020
The purpose of the study is to analyse the system of attracting young professionals to the modern companies in order to reveal their potential. The relevance has been substantiated and the advantages of this area have been noted in the article.
O. S. Suvalov, T. V. Suvalova
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Point Defect Influence on Electrical Conductivity of Semiconducting Ferroelectric AlScN

Ceramics
Aluminum scandium nitride (Al1−xScxN) is a promising ferroelectric material for non-volatile random-access memory devices and electromechanical sensors.
Xiaoman Zhang, Wangwang Xu, Bipin Bhattarai, Dominic A. Dalba, Dilan M. Gamachchi, Indeewari M. Karunarathne, Yue Yu, Nathan J. Pravda, Ruotian Gong, David Stalla, Chong Zu, W. J. Meng, Andrew C. Meng   +12 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Using Spinodal Decomposition to Investigate Diffusion Enhancement and Vacancy Population

Advanced Science
Material sustainability requires energy‐efficient and rapid strengthening processes. In alloys, strengthening through diffusion‐driven precipitation is limited by the low vacancy concentration, with fewer than one vacancy per 100 billion lattice sites at
Xinren Chen, Frédéric De Geuser, Alisson Kwiatkowski da Silva, Chuanlai Liu, Eric Woods, Dirk Ponge, Baptiste Gault, Dierk Raabe   +7 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Vacancy-Induced Semiconductor–Insulator–Metal Transitions in Nonstoichiometric Nickel and Tungsten Oxides

, 2016
Metal–insulator transitions in strongly correlated oxides induced by electrochemical charging have been attributed to formation of vacancy defects. However, the role of native defects in affecting these transitions is not clear.
Ajinkya Puntambekar (3195072), Vidhya Chakrapani (2190244), Qi Wang (22418)   +2 more
core   +1 more source