Results 121 to 130 of about 1,215,047 (334)

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Identification of a small molecule that primes the type I interferon response to cytosolic DNA

Scientific Reports, 2017
The type I interferon response plays a pivotal role in host defense against infectious agents and tumors, and promising therapeutic approaches rely on small molecules designed to boost this system.
Samira Khiar, Marianne Lucas-Hourani, Sébastien Nisole, Nikaïa Smith, Olivier Helynck, Maryline Bourgine, Claude Ruffié, Jean-Philippe Herbeuval, Hélène Munier-Lehmann, Frédéric Tangy, Pierre-Olivier Vidalain   +10 more
doaj   +1 more source

Human Papillomavirus Infection: Prevention, Barriers to Vaccination, and the Need for Education [PDF]

, 2016
While there is no known cure for HPV, prophylactic vaccination provides an effective method of primary prevention against HPV-related diseases. However, many females and males never receive the HPV vaccine as recommended.
Kessler, Theresa A
core   +2 more sources

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

Advanced Functional Materials, EarlyView.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel, Maria Alessandra Martini, Marius Stoeckle, Annika J. Weber, Kersten S. Rabe, Christof M. Niemeyer   +5 more
wiley   +1 more source

Measles vaccination in lung transplant candidates

Frontiers in Immunology
BackgroundThe incidence of measles is now increasing. Measles is especially dangerous for high-risk individuals, including lung transplant candidates with severe progressive bronchopulmonary disorders.ObjectiveThe objective of this study was to ...
Мikhail P. Kostinov, Мikhail P. Kostinov, Valentina B. Polishchuk, Аleksey А. Ryzhov, Pavel I. Zhuravlev, Natalia A. Karchevskaya, Evgeniy A. Tarabrin, Irina L. Solovieva, Alexander P. Cherdantsev, Izabella A. Khrapunova, Elena P. Foshina   +10 more
doaj   +1 more source

mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant

, 2021
Helen Parry, Gokhan Tut, Rachel Bruton, Sian Faustini, Christine Stephens, Philip Saunders, Christopher Bentley, Katherine Hilyard, Kevin Brown, Gayatri Amirthalingam, Sue Charlton, Stephanie Leung, Emily Chiplin, Naomi S. Coombes, Kevin R. Bewley, Elizabeth J. Penn, Cathy Rowe, Ashley Otter, Rosie Watts, Silvia D’Arcangelo, Bassam Hallis, Andrew Makin, Alex Richter, Jianmin Zuo, Paul Moss   +24 more
openalex   +1 more source

Wafer‐Scale Integration of α‐quartz Thin Films toward Super High Frequency Piezoelectric bioNEMS for Chikungunya Virus Detection

Advanced Functional Materials, EarlyView.
Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar, Sijie Ding, David Sanchez‐Fuentes, Claire Jolly, Charlotte André‐Arpin, Rudy Desgarceaux, Nicolas Guillaume, Gustavo Ardila, Ricardo Garcia‐Bermejo, Jaume Gazquez, Sergi Plana‐Ruiz, Laura Picas, Adrian Carretero‐Genevrier   +12 more
wiley   +1 more source

Fractional Dynamics of Vector-Borne Infection with Sexual Transmission Rate and Vaccination [PDF]

, 2021
Shah Hussain, Elissa Nadia Madi, Naveed Iqbal, Thongchai Botmart, Yeliz Karaca, Wael W. Mohammed   +5 more
openalex   +1 more source

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

Time trends in social contacts of individuals according to comorbidity and vaccination status, before and during the COVID-19 pandemic [PDF]

, 2022
Aurélie Godbout, Mélanie Drolet, Myrto Mondor, Marc Simard, Chantal Sauvageau, Gaston De Serres, Marc Brisson   +6 more
openalex   +1 more source