Results 331 to 340 of about 1,319,551 (375)

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

Advanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi, Claudia Corbo, Julia Enterria‐Rosales, John Otto Martinez, Silvia Minardi, Laura Pandolfi, Xing Wang, Ennio Tasciotti, Kavindra V. Singh, Cesar A. Arias, Bruna Corradetti   +10 more
wiley   +1 more source

Predictors affecting vaccine hesitancy towards annual COVID-19 booster shots among populations from different countries. [PDF]

BMC Public Health
Gaber SN, Wahed WYA, Abrokwah BJ, Hawamdeh MIA, Elsidigg LA, Wegdan AA, Bassyouni RH.   +6 more
europepmc   +1 more source

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

Advanced Science, EarlyView.
The salivary sheath protein myosin from SBPH is critical for the formation of the salivary sheath and feeding. However, myosin functions as a HAMP and triggered plant BAK1‐mediated PTI responses, which include the activation of calcium signaling pathways, MAPK phosphorylation, ROS bursts, and cell death, thereby triggering JA pathway.
Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A. Hoffmann, Jichao Fang, Rui Ji   +12 more
wiley   +1 more source

Optimizing HPV vaccine effectiveness: impact of vaccination age and dose schedule on immunogenicity and cervical cancer prevention. [PDF]

Front Public Health
Rostami Varnousfaderani M, Khoshnazar Z, Zeratie H, Hosseini Koukamari P.   +3 more
europepmc   +1 more source

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

Advanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu, Meicen Wu, Qingyang Lyu, Chang Yang, Ni Fan, Kang Chen, Weiping Wang   +6 more
wiley   +1 more source

Impact of unequal testing on vaccine effectiveness estimates across two study designs: a simulation study. [PDF]

Nat Commun
Bodner K, Wang L, Kustra R, Kwong JC, Sander B, Sbihi H, Irvine MA, Mishra S.   +7 more
europepmc   +1 more source

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Vaccination and its social and behavioural drivers in children with disability in Fiji. [PDF]

BMJ Glob Health
Jahan I, Vakaloloma U, Perera S, Tuibeqa I, Devi R, Volavola L, May W, Wilson D, Tuimabu L, Power R, Woolfenden S, Danchin M, McIntyre S, Smithers-Sheedy H, Badawi N, Macartney K, Khandaker G, Sheel M.   +17 more
europepmc   +1 more source

Regional Alliance for Cervical Cancer Prevention in Eastern Europe and Central Asia: Progressing Towards the Target 1 of the Global Strategy for Cervical Cancer Elimination. [PDF]

Healthcare (Basel)
Ussai S, Seyidov T, Khomasuridze T, UNFPA EECA SRH Focal Points, On Behalf Of The Regional Alliance Group Of Experts On Hpv Vaccination.   +4 more
europepmc   +1 more source

Differences in Mpox and Vaccinia Immunity Induced by Non-Replicating and Replicating Vaccinia-Based Vaccines. [PDF]

Vaccines (Basel)
Abate G, Meza K, Yu Y, Colbert C, Jaunarajs A, Blazevic A, Hoft DF, Frey SE.   +7 more
europepmc   +1 more source