Results 181 to 190 of about 129,361 (307)
A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance
Advanced Science, EarlyView.A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang +9 more
wiley +1 more source
Revista Panamericana de Salud PúblicaObjective. Analyze the impact of the COVID-19 pandemic on influenza vaccination coverage in some countries in the Americas. Methods. This descriptive ecological study included Argentina, Chile, and Uruguay and analyzed information on influenza ...
Pablo Bonvehi +4 more
doaj +1 more source
Advanced Science, EarlyView.RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu +7 more
wiley +1 more source
, 2014 *Out of the 244 participants, 199 (81.6%) had the vaccination cards for their youngest children that were alive, whilst 15 (18.4%) did not have; 234 (95.9%) received most of their vaccinations in regional clinics, 5 (2.0%) hospitals, and 5 (2.0%) from ...
Yuan Tang (406486) +2 more
core +1 more source
Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
Advanced Science, EarlyView.MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
Children's vaccinations play a significant role in public health efforts, particularly in reducing morbidity and mortality rates among children worldwide.
Edward A. Magwe
core +1 more source
Physicians’ attitudes towards human papillomavirus vaccination programme: A systematic review [PDF]
, 2011 Human papillomavirus (HPV) vaccine is a newly introduced vaccine against cervical cancer in adolescent girls. Uptake of the vaccine will be dependent on parental acceptability and physician recommendation.
Franco, Maria F.
core
Advanced Science, EarlyView.A non‐canonical core transcriptional regulatory circuit, composed of ID3, SMAD3, and NR2F2, drives Osimertinib resistance in non‐small cell lung cancer through super‐enhancer‐mediated activation of EPAS1, which couples neuroendocrine differentiation with ferroptosis evasion.
Aochu Liu +15 more
wiley +1 more source
Economic modelling assessment of cervical cancer screening and HPV vaccination in Brazil [PDF]
More than 85% of the global burden of cervical cancer occurs in developing countries, where it is the second most common cancer among women. In Brazil alone, a total of 17,500 new cases and 3,300 deaths of cervical cancer are expected in 2012.
Vanni, Tazio
core +1 more source