Results 231 to 240 of about 1,424,765 (382)

Ascites circRNA ASCOR Drives Platinum Resistance of High‐Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation

open access: yesAdvanced Science, EarlyView.
High‐grade serous ovarian carcinoma (HGSOC) is plagued by platinum resistance, with malignant ascites closely linked to poor outcomes. Here, we identify ASCOR, a circRNA enriched in ascites small extracellular vesicles (sEVs) from platinum‐resistant HGSOC patients, as a predictor of poor survival. ASCOR enhances platinum resistance in vitro and in vivo
Hanyuan Liu   +10 more
wiley   +1 more source

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

open access: yesAdvanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang   +6 more
wiley   +1 more source

Perceived Threat of COVID-19 and Vaccination Coverage Among Nurses: A Multicentre Cross-Sectional Study. [PDF]

open access: yesNurs Open
Moreno-Martínez M   +7 more
europepmc   +1 more source

Weekly COVID-19 Vaccination Coverage among Pregnant Women by Race and Ethnicity

open access: green
United States Department of Health and Human Services. Centers for Disease Control and Prevention   +1 more
openalex   +1 more source

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

open access: yesAdvanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang   +9 more
wiley   +1 more source

Interventions to improve pneumococcal vaccination coverage: A systematic review and meta-analysis. [PDF]

open access: yesInfect Med (Beijing)
Cireașă B   +5 more
europepmc   +1 more source

Vaccination Coverage among Nursing Home Residents

open access: green
United States Department of Health and Human Services. Centers for Disease Control and Prevention   +1 more
openalex   +1 more source

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