Results 241 to 250 of about 222,471 (336)

ITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.
Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng   +12 more
wiley   +1 more source

Trends in vaccination coverage and equity in the Democratic Republic of the Congo from 2017 to 2023. [PDF]

Vaccine
Lankiewicz E, Mpemba JKN, Dikassa PSL, Masiala VM, Maykondo BK, Hatton T, Nawaz S, Munar W, Arsenault C.   +8 more
europepmc   +1 more source

Vaccination Coverage among Nursing Home Residents

United States Department of Health and Human Services. Centers for Disease Control and Prevention, Vaccinations   +1 more
openalex   +1 more source

The Impact of COVID-19 on DTP3 Vaccination Coverage in Europe (2012–2023) [PDF]

Inés Aguinaga-Ontoso, Sara Guillén-Aguinaga, Laura Guillén-Aguinaga, Rosa Alas-Brun, Miriam Guillen-Aguinaga, Luc Onambele, Enrique Aguinaga-Ontoso, Esperanza Rayón-Valpuesta, Francisco Guillén‐Grima   +8 more
openalex   +1 more source

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source

Interventions to Improve Adolescent Vaccination Coverage [PDF]

Journal of Adolescent Health, 2015
openaire   +2 more sources

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

The decrease in childhood vaccination coverage and its sociodemographic determinants, the Netherlands, birth cohorts 2008 to 2020. [PDF]

Euro Surveill
Pijpers J, van Roon A, Schipper M, Stok M, van den Hof S, van Gaalen R, Hahné S, de Melker H.   +7 more
europepmc   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Global socioeconomic inequalities in vaccination coverage, supply, and confidence. [PDF]

NPJ Vaccines
Wang Q, Leung K, Jit M, Wu JT, Lin L.
europepmc   +1 more source