Results 51 to 60 of about 114,091 (265)

Utilizing the Metastability of Spidroins as a Strategy for Improving Mechanical Properties of Biomimetic Spider Silk Fibers

open access: yesAdvanced Functional Materials, EarlyView.
Phase transitions are central for the assembly of recombinant silk proteins into fibers. Soluble protein can transition into condensed states such as condensates and gels. These states are metastable and evolve in a time‐dependent way. Metastability depends on the protein sequence, and this relationship can be used to enhance the mechanical properties ...
Fred‐Eric Sammalisto   +5 more
wiley   +1 more source

A review of childhood rotavirus vaccination policies and a presentation of vaccine coverage trends at national and regional level, Italy, 2016 to 2023

open access: yesEurosurveillance
BACKGROUND Rotavirus is a main gastroenteritis cause in children ≤ 5 years old. In 2017, when few Italian regions had rotavirus vaccination programmes, rotavirus vaccines were included in the National Plan for Preventive Vaccination (PNPV).
Leonardo Villani
doaj   +1 more source

The Brazilian vaccine divide: How some municipalities were left behind in the Covid-19 vaccine coverage.

open access: yesPLOS Global Public Health, 2023
This study aims to assess the progress of geographic, socioeconomic, and demographic disparities in Covid-19 vaccination coverage in Brazil over the first two years of the vaccination campaign.
Antonio Fernando Boing   +4 more
doaj   +1 more source

Improving vaccine coverage in adolescence and beyond [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2017
High vaccine coverage is required to ensure population protection, including protection of those that cannot receive vaccines either due to contraindications or age. Despite this, some areas continue to report low vaccine coverage. Reasons for this may vary but can include factors such as difficulties accessing services, conflicting priorities and ...
openaire   +3 more sources

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

open access: yesAdvanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han   +4 more
wiley   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Measles Vaccination Coverage and Anti-Measles Herd Immunity Levels in the World and WHO Regions Worsened from 2019 to 2023

open access: yesVaccines
Objectives: The objectives of this study were as follows: to determine mean percentages of measles vaccination coverage with zero, one and two doses of vaccine and anti-measles herd immunity levels in World Health Organization (WHO) regions in 2023; to ...
Pedro Plans-Rubió
doaj   +1 more source

Reminder design and childhood vaccination coverage

open access: yesJournal of Health Economics
A major policy concern across public vaccination programs is non-compliance. Exploiting Danish population data and three national reforms in regression discontinuity designs, we document the effects of reminders for childhood vaccination coverage. Retrospective reminders are primarily effective for families with small children and when sent out close ...
Hirani, Jonas Cuzulan, Wüst, Miriam
openaire   +5 more sources

Global Routine Vaccination Coverage, 2015 [PDF]

open access: yesMMWR. Morbidity and Mortality Weekly Report, 2016
In 1974, the World Health Organization (WHO) established the Expanded Program on Immunization* to provide protection against six vaccine-preventable diseases through routine infant immunization (1). Based on 2015 WHO and United Nations Children's Fund (UNICEF) estimates, global coverage with the third dose of diphtheria-tetanus-pertussis vaccine (DTP3),
Rebecca M, Casey   +6 more
openaire   +2 more sources

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu   +7 more
wiley   +1 more source

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