Results 71 to 80 of about 283,427 (308)

Validation of the Vaccination Trust Indicator (VTI) in a multi-country survey of adult vaccination attitudes

PLOS Global Public Health, 2023
Improved uptake of adult vaccinations could substantially reduce the burden of infectious disease worldwide, however very few countries achieve high coverage of recommended adult vaccinations. Vaccine hesitancy is an important driver of low vaccine uptake among adults but no measure currently exists to capture general vaccination attitudes in this ...
Mallory K. Ellingson, Saad B. Omer, Nick Sevdalis, Angus Thomson   +3 more
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

POSSIBILITIES OF ENHANCEMENT OF VACCINE PROPHYLAXIS IN CONTEMPORARY RUSSIA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Discussing the situation regarding coverage of adult population with prophylaxis vaccines at contemporary stage, we propose novel approaches of enhancement of vaccination, taking into consideration realities of the present day.
M. P. Kostinov, I. V. Lukachev
doaj   +1 more source

Tetanus–diphtheria–acellular pertussis vaccination of adults in the USA

Expert Review of Vaccines, 2008
Pertussis is an important cause of morbidity and mortality, and its incidence has been increasing in adolescents and adults over the past two decades. Waning immunity in adolescents and adults may be partially responsible. Adults can suffer significant illness from pertussis and its complications, such as pneumonia, rib fractures and syncope. Moreover,
Courtney A, Gidengil, Thomas J, Sandora, Grace M, Lee   +2 more
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Exploring Perceptions and Practices Regarding Adult Vaccination against Seasonal Influenza, Tetanus, Pneumococcal Disease, Herpes Zoster and COVID-19: A Mixed-Methods Study in Greece

Vaccines
We aimed to document vaccination coverage for five vaccines, predictors of each vaccine’s uptake and attitudes regarding adult vaccination. Adults visiting four pharmacies were randomly invited to participate during summer 2022.
Iordanis Avramidis, Ilias Pagkozidis, Philippe-Richard J. Domeyer, Georgios Papazisis, Ilias Tirodimos, Theodoros Dardavesis, Zoi Tsimtsiou   +6 more
doaj   +1 more source

Association between Adult Vaccine Hesitancy and Parental Acceptance of Childhood COVID-19 Vaccines: A Web-Based Survey in a Northwestern Region in China

Vaccines, 2021
China has initiated the COVID-19 vaccination for children aged 15–17 years since late July 2020. This study aimed to determine the association between adult vaccine hesitancy and parental acceptance of childhood COVID-19 vaccines in a multi-ethnicity ...
Kezhong A, Xinyue Lu, Jing Wang, Linjie Hu, Bingzhe Li, Yihan Lu   +5 more
doaj   +1 more source

Cost-Effectiveness of Pneumococcal Vaccines for Adults in the United States [PDF]

Advances in Therapy, 2013
In 2012, the Advisory Committee on Immunization Practices (ACIP) revised recommendations for adult pneumococcal vaccination to include a sequential regimen of 13-valent pneumococcal conjugate vaccine (PCV13) followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23) for certain high-risk adults with immunocompromising conditions.
Chen, Jieling, O’Brien, Megan A., Yang, H. Keri, Grabenstein, John D., Dasbach, Erik J.   +4 more
openaire   +3 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Barriers to effective communication on adult vaccination: results of in-depth interviews with the population and healthcare professionals of the Arkhangelsk Oblast

Кардиоваскулярная терапия и профилактика
The effectiveness of communication with a doctor on vaccination often determines a patient's decision to vaccinate. However, the related difficulties and barriers remain insufficiently studied.Aim.
M. V. Lopatina, E. A. Kriger, N. R. Nizovtseva, A. V. Kudryavtsev, V. A. Yakovleva, V. А. Zinovieva, E. V. Usova, A. V. Kontsevaya, O. M. Drapkina   +8 more
doaj   +1 more source