Results 171 to 180 of about 2,206,632 (403)
Cost and operational context for national human papillomavirus (HPV) vaccine delivery in six low- and middle-income countries
, 2023 Mercy Mvundura, Rose Slavkovsky, Frédéric Debellut, Teddy Naddumba, Amare Bayeh, Cathy Ndiaye, Jacqueline Anena, Elisabeth Vodicka, Abdou Khoudia Diop, Deepa Gamage, Clarisse Musanabaganwa, Ganesh Tatkan, Alfred Driwale, Meseret Zelalem, Ousseynou Badiane, Samitha Ginige, Ertenisa Hamilton, Hassan Sibomana, Yohannes Lakew, François Uwinkindi, Adugna Dhufera, Immaculate Ampeire, Sandeep Kumar, D. Scott LaMontagne +23 moreopenalex +1 more sourceEvaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection
Advanced Healthcare Materials, EarlyView.This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann +12 morewiley +1 more sourceMicroneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla +3 morewiley +1 more sourceHighly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication
Advanced Healthcare Materials, EarlyView.Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...Julia Fernández‐Pérez, Adrián Seijas‐Gamardo, Antonio J. Feliciano, Panagiota Kakni, Anna M. Kip, Paul Wieringa, Stefan Giselbrecht, Matthew B. Baker, Lorenzo Moroni +8 morewiley +1 more sourcePreclinical characterization of the Omicron XBB.1.5-adapted BNT162b2 COVID-19 vaccine
npj VaccinesAs SARS-CoV-2 evolves, increasing in potential for greater transmissibility and immune escape, updated vaccines are needed to boost adaptive immunity to protect against COVID-19 caused by circulating strains.Kayvon Modjarrad, Ye Che, Wei Chen, Huixian Wu, Carla I. Cadima, Alexander Muik, Mohan S. Maddur, Kristin R. Tompkins, Lyndsey T. Martinez, Hui Cai, Minah Ramos, Sonia Mensah, Brittney Cumbia, Larissa Falcao, Andrew P. McKeen, Jeanne S. Chang, Kimberly F. Fennell, Kevin W. Huynh, Thomas J. McLellan, Parag V. Sahasrabudhe, Wei Chen, Michael Cerswell, Miguel A. Garcia, Shilong Li, Rahul Sharma, Weiqiang Li, Kristianne P. Dizon, Stacy Duarte, Frank Gillett, Rachel Smith, Deanne M. Illenberger, Kari Sweeney Efferen, Annette B. Vogel, Annaliesa S. Anderson, Uğur Şahin, Kena A. Swanson +35 moredoaj +1 more sourceInactivated Rabies Virus–Based Ebola Vaccine Preserved by Vaporization Is Heat-Stable and Immunogenic Against Ebola and Protects Against Rabies Challenge [PDF]
, 2019 Drishya Kurup, Christine R. Fisher, Thomas A. Smith, Tiago Abreu-Mota, Yong Yang, Felix R. Jackson, Nadia Gallardo‐Romero, Richard Franka, Victor Bronshtein, Matthias J. Schnell +9 moreopenalex +1 more source