Results 191 to 200 of about 1,325,849 (308)

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

The Current Landscape and Future Prospects of Vaccine Manufacturing in Africa: Challenges, Innovations, and Opportunities: A Narrative Review. [PDF]

Health Sci Rep
Chandipwisa C, Shimilimo A, Uwishema O, Onyeaka H.   +3 more
europepmc   +1 more source

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source

Hepatitis B Vaccine Response in Children of Vaccinated Versus Unvaccinated Mothers: A Retrospective Cohort Study. [PDF]

J Viral Hepat
Shibli S, Suki M, Korzom T, Green MS, Safadi R.   +4 more
europepmc   +1 more source

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, EarlyView.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation

Advanced Science, EarlyView.
Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah, Denver P. Linklater, Vassil Tzanov, Chaitali Dekiwadia, Sergey Rubanov, Phuc H. Le, Laleh Tafakori, Ranya Simons, Graeme Moad, Soichiro Saita, Takashi Yanagishita, Hideki Masuda, Vladimir Baulin, Natalie A. Borg, Elena P. Ivanova   +14 more
wiley   +1 more source

Combination of adenovirus vector and subunit protein elicits a robust immune response against the SARS-CoV-2 Omicron variant. [PDF]

Mol Biomed
Ye C, Huang X, Hong W, Shi J, Ao D, Zhang Y, Lu Y, Zhou Y, Song Z, Zhang Y, Liu Y, Cheng P, Lu G, Li J, Song X, Wei X.   +15 more
europepmc   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Correction: Neutrophil killing of Staphylococcus aureus in diabetes, obesity and metabolic syndrome: a prospective cellular surveillance study

Diabetology & Metabolic Syndrome
Ingrid Lea Scully, Lisa Kristin McNeil, Sudam Pathirana, Christine Lee Singer, Yongdong Liu, Stanley Mullen, Douglas Girgenti, Alejandra Gurtman, Michael W. Pride, Kathrin Ute Jansen, Paul L. Huang, Annaliesa S. Anderson   +11 more
doaj   +1 more source

A Monoclonal Antibody ELISA-Based Assay for Measuring the Potency of Candidate H5 Clade 2.3.4.4b Pandemic Influenza Vaccines. [PDF]

Influenza Other Respir Viruses
Odin M, Schmeisser F, Soto J, Weir JP.
europepmc   +1 more source