Results 211 to 220 of about 2,114,452 (380)
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma+9 more
wiley +1 more source
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
wiley +1 more source
Discussion on Vaccines from the Standpoint of the Physician
Thomas Horder
openalex +1 more source
Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae+6 more
wiley +1 more source
Preclinical immunogenicity and safety of hemagglutinin-encoding modRNA influenza vaccines
Seasonal epidemics of influenza viruses are responsible for a significant global public health burden. Vaccination remains the most effective way to prevent infection; however, due to the persistence of antigenic drift, vaccines must be updated annually.
Teresa Hauguel+28 more
doaj +1 more source
Gonococcus Vaccines and Glycerine Extracts of the Gonococcus in the Diagnosis of Gonorrheal Infections [PDF]
George Cheever Shattuck+1 more
openalex +1 more source
GMO cubosomes and DOPE hexosomes interact differently with lipid membranes: cubosomes exchange lipid molecules with the membranes, destabilizing them when the membranes do not contain cholesterol. Hexosomes interact more gently with membranes and tend to fuse and incorporate into them.
Mario Campana+4 more
wiley +1 more source
FURTHER RESEARCHES ON DETOXICATED VACCINES [PDF]
David I. C. Thomson, Rachael Thomson
openalex +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source