Results 261 to 270 of about 2,114,452 (380)

An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W.H. Zhang, Xiaopeng Ma, Hui Tan, George F. Gao, Shuguang Tan   +14 more
wiley   +1 more source

An immunogenic personal neoantigen vaccine for patients with melanoma

Nature, 2017
P. Ott, Zhuting Hu, D. Keskin, S. Shukla, Jing Sun, David j. Bozym, Wandi Zhang, Adrienne M. Luoma, A. Giobbie-Hurder, Lauren Peter, Christina Chen, Oriol Olive, T. Carter, Shuqiang Li, David J. Lieb, T. Eisenhaure, E. Gjini, Jonathan D. Stevens, W. Lane, I. Javeri, K. Nellaiappan, A. Salazar, H. Daley, Michael G. Seaman, E. Buchbinder, Charles H. Yoon, M. Harden, N. Lennon, S. Gabriel, S. Rodig, D. Barouch, J. Aster, G. Getz, K. Wucherpfennig, D. Neuberg, J. Ritz, E. Lander, E. Fritsch, N. Hacohen, Catherine J. Wu   +39 more
semanticscholar   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source

A qualitative study on barriers and facilitators of COVID-19 vaccination during pregnancy among pregnant women in Malaysia. [PDF]

PLoS One
Mohamed Pauzi MH, Abdul Kadir A, Muhamad R, Mat Yudin Z.   +3 more
europepmc   +1 more source

THE TREATMENT OF PERTUSSIS WITH VACCINE [PDF]

, 1912
Edwin E. Graham
openalex   +1 more source

Vaccine and Vaccination

American Journal of Public Health and the Nations Health, 1930
openaire   +3 more sources

An Anisotropic Gold‐Palladium Heterostructured Nanosystem for Synergistically Overcoming Radioresistance and Enhancing Melanoma Radioimmunotherapy

Advanced Science, EarlyView.
A multifunctional anisotropic Au‐Pd heterostructured nanosystem is developed that incorporates a plasmonically enhanced Au‐Pd core, with a shell composed of a biodegradable, Mn‐doped targeting peptide. The nanosystem integrates photothermal, radiotherapeutic, and immunomodulatory functions.
Cheng Chen, Yuqi Huang, Wandong Wang, Minghao Chao, Weiguo Sun, Yinghui Kong, Guan Jiang, Yong Gao, Fenglei Gao   +8 more
wiley   +1 more source

The Treatment of Bronchial Asthma with Vaccines [PDF]

, 1919
Ian Walker
openalex   +1 more source

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

Willingness to pay and preference for HPV vaccine among parents in China: A study based on a multi-center cross-sectional survey. [PDF]

Hum Vaccin Immunother
Luo W, Wang D, Qin R, Xu G, Zhou L.
europepmc   +1 more source