Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution
Partial Replacement of phospholipid lipid by cationic lipid improves storage stability of commercial mRNA LNPs by stabilizing their internal microstructure. Abstract Messenger RNA lipid nanoparticles (mRNA‐LNPs) have achieved remarkable success in clinical vaccination efforts to curb the COVID‐19 pandemic, and have attracted tremendous interest from ...
Rui Chen +8 more
wiley +1 more source
Dengue vaccine effectiveness and safety: a systematic analysis of recent clinical trial data. [PDF]
Kant R +5 more
europepmc +1 more source
Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing
This article presents the first mechanistic model for continuous lyophilization (aka freeze drying). The model accurately describes the key phenomena and critical process parameters in continuous lyophilization, which can be used for process design, optimization, and control. Results from this work can drive the transition of (bio)pharmaceutical freeze
Prakitr Srisuma +2 more
wiley +1 more source
RE-AIM evaluation of a community-based vaccine education and communication program to improve human papillomavirus vaccine uptake in Tonga. [PDF]
Mohamed Y +18 more
europepmc +1 more source
From allergen to oral vaccine carrier: A new face of ragweed pollen
Md Jasim Uddin, Harvinder Singh Gill
openalex +2 more sources
This review summarizes the design principles and key features of programmable hydrogels that respond to multiple stimuli. It then delves into the cutting‐edge mechanisms of self‐executing systems, highlighting their role as the cornerstone of next‐generation programmable hydrogels (NGPHs).
Guangli Xiang +8 more
wiley +1 more source
Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025. [PDF]
Irving SA +36 more
europepmc +1 more source
Whole-Genome Sequences of Four Mycobacterium bovis BCG Vaccine Strains
Yuanlong Pan +15 more
openalex +2 more sources
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
Properties and performance of a questionnaire assessing COVID-19 vaccine knowledge and attitudes in Brazilian pregnant women. [PDF]
Maudonnet B +19 more
europepmc +1 more source

