Results 311 to 320 of about 2,182,415 (399)

Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution

open access: yesAdvanced Science, EarlyView.
Partial Replacement of phospholipid lipid by cationic lipid improves storage stability of commercial mRNA LNPs by stabilizing their internal microstructure. Abstract Messenger RNA lipid nanoparticles (mRNA‐LNPs) have achieved remarkable success in clinical vaccination efforts to curb the COVID‐19 pandemic, and have attracted tremendous interest from ...
Rui Chen   +8 more
wiley   +1 more source

Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing

open access: yesAdvanced Science, EarlyView.
This article presents the first mechanistic model for continuous lyophilization (aka freeze drying). The model accurately describes the key phenomena and critical process parameters in continuous lyophilization, which can be used for process design, optimization, and control. Results from this work can drive the transition of (bio)pharmaceutical freeze
Prakitr Srisuma   +2 more
wiley   +1 more source

RE-AIM evaluation of a community-based vaccine education and communication program to improve human papillomavirus vaccine uptake in Tonga. [PDF]

open access: yesPLOS Glob Public Health
Mohamed Y   +18 more
europepmc   +1 more source

Programmable Hydrogels: Frontiers in Dynamic Closed‐Loop Systems, Biomimetic Synergy, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
This review summarizes the design principles and key features of programmable hydrogels that respond to multiple stimuli. It then delves into the cutting‐edge mechanisms of self‐executing systems, highlighting their role as the cornerstone of next‐generation programmable hydrogels (NGPHs).
Guangli Xiang   +8 more
wiley   +1 more source

Effectiveness of 2024-2025 COVID-19 Vaccines in Children in the United States - VISION, August 29, 2024-September 2, 2025. [PDF]

open access: yesMMWR Morb Mortal Wkly Rep
Irving SA   +36 more
europepmc   +1 more source

Whole-Genome Sequences of Four Mycobacterium bovis BCG Vaccine Strains

open access: green, 2011
Yuanlong Pan   +15 more
openalex   +2 more sources

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

Properties and performance of a questionnaire assessing COVID-19 vaccine knowledge and attitudes in Brazilian pregnant women. [PDF]

open access: yesBMC Public Health
Maudonnet B   +19 more
europepmc   +1 more source

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