Results 221 to 230 of about 330,204 (355)

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Influenza Vaccine Effectiveness in Korea: A Systematic Review and Meta-Analysis of Real-World Evidence from the Past Decade. [PDF]

Vaccines (Basel)
Jeong HS, Kim HY.
europepmc   +1 more source

PIN24 THE COST-EFFECTIVENESS OF 23-VALENT PNEUMOCOCCAL VACCINE IN CATALONIA, SPAIN

, 2003
Pedro Plans-Rubió
openalex   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Evaluation of hepatitis B vaccine effectiveness among fully vaccinated healthcare workers in Ethiopia. [PDF]

BMC Infect Dis
Adugna A, Amare GA, Muche Y, Getinet M, Melkamu A, Dilnessa T, Malik T, Belew H, Jemal M, Abebaw D.   +9 more
europepmc   +1 more source

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Dengue vaccine effectiveness and safety: a systematic analysis of recent clinical trial data. [PDF]

Virol J
Kant R, Singh A, Ali AB, Nagre S, Ganguly NK, Rana R.   +5 more
europepmc   +1 more source

The population-level impact of bivalent HPV vaccination on closely related non-vaccine types [PDF]

, 2018
Kavanagh, Kimberly, Mesher, David, Pollock, Kevin   +2 more
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Influenza vaccine effectiveness among adults aged ≥60 years in northeastern Zhejiang Province, China, 2021-2024. [PDF]

Front Public Health
Yu Z, Liu X, Fu J, Yang X, Liu Y, Chu Y, Jin J, Xu Z, Cao Y, Pan J, Liu S, Fu X, He T, Zhang H.   +13 more
europepmc   +1 more source