Results 251 to 260 of about 330,204 (355)

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Estimated Vaccine Effectiveness for Respiratory Syncytial Virus-Related Acute Respiratory Illness in Older Adults: Findings From the First Postlicensure Season. [PDF]

Clin Infect Dis
Tartof SY, Aliabadi N, Goodwin G, Slezak J, Hong V, Ackerson B, Liu Q, Shaw S, Welsh S, Kapadia B, Spence BC, Lewnard JA, Davis GS, Aragones M, Dutro M, Chilson E, Gonzalez E, Hubler R, Jodar L, Gessner BD, Begier E.   +20 more
europepmc   +1 more source

Effectiveness of Enterovirus 71 inactivated vaccines against hand, foot, and mouth disease: A test-negative case-control study [PDF]

Yutong Zhang, Jinzhao Cui, Fengfeng Liu, Yang Song, Quanyi Wang, Yanzhe Liu, Yanping Zhang, Zhongjie Li, Zhaorui Chang   +8 more
openalex   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

Does Home COVID-19 Testing Bias COVID-19 Vaccine Effectiveness Estimates? [PDF]

Am J Prev Med
Nowalk MP, Balasubramani GK, D'Agostino H, Zimmerman RK, Monto AS, Martin ET, Nguyen HQ, Gaglani M, Mamawala M, Tartof S, Lewin BJ, Wernli K, Wickersham B, Talbot HK, Grijalva CG, Chung JR, Flannery B, U.S. Flu VE Network Investigators.   +17 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Influenza Vaccine Effectiveness Against Medically Attended Outpatients Illness, United States, 2023-2024 Season. [PDF]

Clin Infect Dis
Chung JR, Price AM, Zimmerman RK, Moehling Geffel K, House SL, Curley T, Wernli KJ, Phillips CH, Martin ET, Vaughn IA, Murugan V, Scotch M, Saade EA, Faryar KA, Gaglani M, Ramm JD, Williams OL, Walter EB, Kirby MK, Keong LM, Kondor R, Ellington SR, Flannery B.   +22 more
europepmc   +1 more source

Factors associated with COVID-19 in-hospital death and COVID-19 vaccine effectiveness against COVID-19 hospitalization in the Philippines during pre-omicron and omicron period: A case-control study (MOTIVATE-P study) [PDF]

Takeshi Arashiro, Rontgene Solante, Ana Ria Sayo, Rosa Millán García, Mark G. Kris, Shuichi Suzuki, Greco Mark Malijan, Mary Jane Salazar, M. Salazar, Abby Ortal-Cruz, Grace Devota Go, Edna Miranda, Michelle Carandang-Cuvin, Joy Potenciano Calayo, Jinho Shin, Martin L. Hibberd, Koya Ariyoshi, Chris Smith   +17 more
openalex   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

Advanced Science, EarlyView.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang, Wenjing Xu, Yafang Lu, Huaibin Yu, Zhengbao Zha, Xijun Zhang   +5 more
wiley   +1 more source

Precautionary Health Behaviours as Potential Confounders in COVID-19 Vaccine Effectiveness Studies. [PDF]

Vaccines (Basel)
Wyndham-Thomas C, de Munter L, Ngew KY, Gaikwad S, Chatzikonstantinidou K, Carmona A, Martin C, Ten Kate GL, Praet N, Meeraus W, Rousculp MD, Bollaerts K.   +11 more
europepmc   +1 more source