Results 231 to 240 of about 2,444,578 (297)

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Classification of risk for transmission of vaccine-preventable diseases in Brazilian municipalities: comparative analysis before and after the national movement for vaccination and multivaccination proposed by the Ministry of Health as of 2023. [PDF]

BMC Public Health
de Melo Araújo AC, da Silva TPR, Souza JFA, Freire KMR, Matozinhos FP, Fernandes EG.   +5 more
europepmc   +1 more source

Special Populations in Pivotal Clinical Trials: Eligibility and Supporting Evidence for Exclusion in EMA‐Authorised Medicines

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence on the efficacy and safety of medicines supporting marketing authorization is largely derived from randomized controlled trials, yet these trials often exclude populations likely to use the medications in clinical practice. This study assessed eligibility of special populations, defined as pregnant and breast‐feeding individuals, elderly ...
Maja J. Jørgensen, Débora D. Gräf, Christine E. Hallgreen   +2 more
wiley   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Cost of illness of the vaccine-preventable diseases influenza, herpes zoster and pneumococcal disease in France. [PDF]

Eur J Public Health
Brown L, Sutton KJ, Browne C, Bartelt-Hofer J, Greiner W, Petitjean A, Roiz J.   +6 more
europepmc   +1 more source

2022 Polio outbreak, Rockland County, NY: Cost evaluation of strategies to prevent future outbreaks of vaccine-preventable diseases. [PDF]

Vaccine
Pike J, Lueken J, Zajac J, Tippins A, Doss S, De Coteau A, Punjabi C, Souto M, Bhatt A.   +8 more
europepmc   +1 more source

Investigating sources of non-response bias in a population-based seroprevalence study of vaccine-preventable diseases in the Netherlands. [PDF]

BMC Infect Dis
Postema A, Ferreira JA, van der Klis F, de Melker H, Mollema L.   +4 more
europepmc   +1 more source