Results 281 to 290 of about 850,017 (337)

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Effects of inactivated COVID-19 vaccination on HIV viremia and reservoir size: a longitudinal cohort study. [PDF]

BMC Infect Dis
Li J, Guo C, Xin R, Deng Y, Pang C, Ye J, Li J, Lu H, He X, Wang Q.   +9 more
europepmc   +1 more source

Effectiveness of COVID‐19 Vaccination in Reducing Severity Among SARS‐CoV‐2 Infected Patients: A Prospective Study From Iraq

Health Science Reports, Volume 9, Issue 2, -Not available-.
ABSTRACT Background Coronavirus disease 2019 (COVID‐19) is a lethal global pandemic that originated in Wuhan, China at the end of 2019. As with other viral infectious diseases, the introduction of an effective vaccine is crucial for stopping the spread of the pandemic. In Iraq the COVID‐19 vaccination campaign started on March 2, 2021.
Ahmed Hakim Al‐Obaidi, Marwan Majeed Ibrahim, Abdul Hameed Abdul Majeed Al‐Qaseer   +2 more
wiley   +1 more source

Virus-like particle-based liquid phase blocking ELISA for evaluating the efficacy of O-type foot-and-mouth disease vaccines. [PDF]

Appl Microbiol Biotechnol
Zhang Y, Wei T, Ren M, Mu S, Bai M, Yin S, Sun S, Guo H, Dong H.   +8 more
europepmc   +1 more source

The Phospholipid Bis(monoacylglycero)Phosphate Confers Antitumour Immunogenicity to Exosomes Secreted by Dendrogenin A, Which Activates Its Biosynthesis in Tumour Cells

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Dendrogenin A stimulates, via LXRβ, the expression and activity of enzymes responsible for the biosynthesis of the phospholipid BMP. BMP is a key determinant of the antitumour immunogenicity of exosomes secreted by DDA‐treated melanoma and triple‐negative breast cancer cells and enhances mouse survival and anti‐PD‐1 therapy in melanoma.
Julio Buñay, Michel Record, Philippe de Medina, Silia Ayadi, Laly Pucheu, Céline Colacios, Bruno Ségui, Marcus Höring, Gerhard Liebisch, Hélène Martin, Marc Poirot, Sandrine Silvente‐Poirot   +11 more
wiley   +1 more source

Atomic Force Microscopy of Poliovirus Particles After Inactivation by Chemical Methods and Accelerated Electrons. [PDF]

Viruses
Kraevsky SV, Kanashenko SL, Kolesnichenko AV, Ivin YY, Piniaeva AN, Kovpak AA, Ishmukhametov AA, Budnik SV, Churyukin RS, Shilov OA, Zhdanov DD.   +10 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Next-Generation Vaccines for Co-Circulating PEDV and TGEV: Integrating Nucleic Acid Platforms, Mucosal Delivery, and AI-Driven Antigen Design. [PDF]

Transbound Emerg Dis
Hu X, Wang Z, Wang S, Sun H, Feng N, Li E, Xia X, Hu G, Yan F, Li B.   +9 more
europepmc   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Mapping Pediatric Seasonal Influenza Vaccine Safety and Immunogenicity Evidence: A Systematic Review of Clinical Trials. [PDF]

Vaccines (Basel)
Munoz A, Olivares B, Yepes-Perez Y, Chen Y, Ortiz J, Amin M, Zeng M.   +6 more
europepmc   +1 more source