Results 231 to 240 of about 702,754 (301)

Clinical and public health economic impact of rapid strain-matched vaccination in influenza pandemic mitigation: A UK-like population dynamic transmission model. [PDF]

Hum Vaccin Immunother
Lovick S, Sudhanva M, Kennedy AT, Longstaff R, Ciglia E, Mould-Quevedo JF.   +5 more
europepmc   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Advances in Therapeutic Melanoma Vaccines (2010-2025). [PDF]

Vaccines (Basel)
Bian MY, Stevens R, Mangla A, Mitra D, Zaorsky NG, Bordeaux JS, Rothermel LD.   +6 more
europepmc   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Immunogenicity evaluation of recombinant rabies virus-vectored multivalent vaccines expressing feline calicivirus VP1 and feline herpesvirus 1 gB/gD genes. [PDF]

Virulence
Wang Y, Wang Y, Zhao S, He H, Li X, Liang Y, Wang J, Xin L, Chen N, Xie W, Huang S, Luo J, Guo X.   +12 more
europepmc   +1 more source

Behavioral Coping With Food Price Inflation: Patterns Among U.S. Households

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Recent food price inflation has placed substantial pressure on household budgets, food security, and mental well‐being. Using Household Pulse Survey data, we combine k‐modes clustering and Double Machine Learning to identify distinct household coping groups and examine differences in how households respond to rising food prices across groups ...
Yuxiang Zhang, Yizao Liu
wiley   +1 more source

Retraction: Exploring the safety and immunogenicity of the VLA15 vaccine among healthy or high-risk population: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Ther Adv Vaccines Immunother
europepmc   +1 more source

Precision immuno-oncology in NSCLC: integrating ADCs, therapeutic vaccines, and adoptive cell therapies for next-generation systemic treatment. [PDF]

Front Oncol
Garg P, Singhal SS.
europepmc   +1 more source

Economic factors promoting vaccine nationalism in the face of viral evolution. [PDF]

PLoS Comput Biol
Freedman AS, Nielsen BF, Saad-Roy CM, Grenfell BT, Metcalf CJE, Levin SA.   +5 more
europepmc   +1 more source

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source