Proposta de formulação intranasal para vacinas bacterianas [PDF]
Anais do V Seminário Anual Científico e Tecnológico de Bio-Manguinhos, 2017 Isabelly Pereira +3 more
exaly +3 more sources
Off balance: Interferons in COVID-19 lung infections [PDF]
EBioMedicine, 2021 Interferons are innate and adaptive cytokines involved in many biological responses, in particular, viral infections. With the final response the result of the balance of the different types of Interferons.
Milena Apetito Akamatsu +3 more
doaj +2 more sources
A New Recombinant Multiepitope Chimeric Protein of Leptospira interrogans Is a Promising Marker for the Serodiagnosis of Leptospirosis [PDF]
Tropical Medicine and Infectious Disease, 2022 The zoonotic disease leptospirosis is caused by pathogenic species of the genus Leptospira and was recently included in the list of Neglected Diseases by the World Health Organization.
Luis G. V. Fernandes +5 more
doaj +2 more sources
A Novel Leptospira interrogans Protein LIC13086 Inhibits Fibrin Clot Formation and Interacts With Host Components [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Leptospirosis is a neglected zoonosis, caused by pathogenic spirochetes bacteria of the genus Leptospira. The molecular mechanisms of leptospirosis infection are complex, and it is becoming clear that leptospires express several functionally redundant ...
Felipe José Passalia +4 more
doaj +2 more sources
A Novel Brighter Bioluminescent Fusion Protein Based on ZZ Domain and Amydetes vivianii Firefly Luciferase for Immunoassays [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 Immunoassays are widely used for detection of antibodies against specific antigens in diagnosis, as well as in electrophoretic techniques such as Western Blotting.
Vadim R. Viviani +4 more
doaj +2 more sources
Immunoprotective Activity Induced by Leptospiral Outer Membrane Proteins in Hamster Model of Acute Leptospirosis [PDF]
Frontiers in Immunology, 2020 Leptospirosis is a zoonotic disease of worldwide distribution, affecting both humans and animals. The development of an effective vaccine against leptospirosis has long been pursued but without success.
Aline F. Teixeira +10 more
doaj +2 more sources
Community‐acquired pneumonia among children: the latest evidence for an updated management [PDF]
Jornal de Pediatria (Versão em Português), 2020 Objective: To provide cutting‐edge information for the management of community‐acquired pneumonia in children under 5 years, based on the latest evidence published in the literature.
Cristiana M. Nascimento‐Carvalho
doaj +5 more sources
Evaluation of Lsa46 and Lsa77 Leptospiral Proteins for Their Immunoprotective Activities in Hamster Model of Leptospirosis. [PDF]
Biomed Res Int, 2018 Leptospirosis is a neglected tropical disease caused by pathogenic Leptospira spp. The lack of an effective vaccine favors the increase of the disease. Currently, surface‐exposed proteins are the main targets for the search of vaccine candidates. In this study, we examined whether the surface Lsa46 and Lsa77 proteins, previously identified as laminin ...
Teixeira AF +6 more
europepmc +2 more sources
Development and characterization of a multimeric recombinant protein using the spike protein receptor binding domain as an antigen to induce SARS‐CoV‐2 neutralization [PDF]
Immunity, Inflammation and DiseaseBackground SARS‐CoV2 virus, responsible for the COVID‐19 pandemic, has four structural proteins and 16 nonstructural proteins. S‐protein is one of the structural proteins exposed on the virus surface and is the main target for producing neutralizing ...
Veronica A. deLima +11 more
doaj +2 more sources
Comportamento imunológico das vacinas anti-meningocócicas
Revista de Saúde Pública, 1997 A doença meningocócica continua sendo um grande problema de saúde pública em todos os continentes, e as vacinas anti-meningocócicas têm sido indicadas na prevenção e controle de epidemias. As vacinas polissacarídicas A e C são relativamente eficazes, com
Henry I. Z. Requejo
doaj +5 more sources