Results 131 to 140 of about 100,194 (263)

Obligatory intracellular bacterium Anaplasma phagocytophilum AnkA regulates actin dynamics and spatiotemporal bacterial release. [PDF]

PLoS Pathog
Lin M, Duan N, Rikihisa Y.
europepmc   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

The profile of clinical and laboratory features of Chinese VEXAS syndrome patients with hematological abnormalities: a single-center case series. [PDF]

Front Immunol
Ren X, Wang M, Huo J, Jia Y, Xiao J, Nie N, Huang J, Zhang J, Zhao X, Fang L, Peng G, Zhang L, Zhang F, Zheng Y, Shi J, Ge M.   +15 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Decoding Cytoplasmic Vacuolization: Unraveling the Diagnostic Challenges of VEXAS Syndrome

Turkish Journal of Hematology
Taner Tan, Mustafa Cem Bülbül, Merve Kaysin, Ibrahim Öner Doğan, Olga Meltem Akay, Sinem Cıvrız Bozdağ   +5 more
doaj   +1 more source

Drug-Free Remission of VEXAS Syndrome Without Stem Cell Transplantation. [PDF]

Cureus
Warren J, Smylie C, Milne A.
europepmc   +1 more source

With Regard to the Expression Status of Sarcolemmal Aquaporin 4 in Human Muscular Dystrophies

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Human muscular dystrophies are inherited muscle‐wasting diseases caused by the various kinds of gene mutations. Among them, Duchenne muscular dystrophy (DMD) is a representative type. Before the discovery of the causative dystrophin gene of DMD, the fragile myofiber plasma membrane was thought to be the trigger of myofiber necrosis in DMD ...
Yoshihiro Wakayama, Takahiro Jimi
wiley   +1 more source

Thymoquinone protects against statin-induced cerebellar damage, apoptosis, and hepatic cytotoxicity in rats. [PDF]

Sci Rep
Ouies SM, Amin YA, Ragab NA, Ismae ZM, Hassany MA, Abd Elhameed BT, Hassan RGM, Mohammed WI, Abd-El Baki Ahmed M.   +8 more
europepmc   +1 more source

Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice

PROTEOMICS, EarlyView.
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min, Choonseok Lee, Ravi Gupta, Gi Hyun Lee, Ji Soo Kim, Na Won Park, Joong Hyoun Chin, Ki‐Hong Jung, Sun Tae Kim   +8 more
wiley   +1 more source

Understanding the Phenotypic Heterogeneity Within the Sporadic Creutzfeldt-Jakob Disease MV1 Subtype. [PDF]

Neuropathol Appl Neurobiol
Nemani SK, Cortez LM, Myskiw J, Cali I, Booth SA, Jansen GH, Sim VL.   +6 more
europepmc   +1 more source