Results 341 to 350 of about 225,485 (404)

A Multi-Index Fusion Adaptive Cavitation Feature Extraction for Hydraulic Turbine Cavitation Detection. [PDF]

Entropy (Basel)
Wang Y, Li F, Lv M, Wang T, Wang X.
europepmc   +1 more source

Progressive sequential development of left and right‐sided idiopathic recurrent laryngeal neuropathy in a Standardbred racehorse

Equine Veterinary Education, EarlyView.
Summary A 4‐year‐old Standardbred racehorse presented to the hospital due to poor performance and abnormal respiratory noises. A high‐speed treadmill videoendoscopic examination including tracheal airway pressure measurements was performed. Grade C left recurrent neuropathy was diagnosed and a prosthetic laryngoplasty was performed.
H. M. B. Olsen, R. Sørby, E. Strand
wiley   +1 more source

Hepatic Steatosis Analysis in Metabolic Dysfunction-Associated Steatotic Liver Disease Based on Artificial Intelligence. [PDF]

Diagnostics (Basel)
Wang XX, Song YY, Jin R, Wang ZL, Li XH, Yang Q, Teng X, Liu FF, Wu N, Xie YD, Rao HY, Liu F.   +11 more
europepmc   +1 more source

Protein import into bacterial endosymbionts and evolving organelles

The FEBS Journal, EarlyView.
The acquisition of bacterial endosymbionts by ancient host cells followed by massive adaptation of the partners gave rise to mitochondria and plastids. Today, various systems with younger and less integrated endosymbionts provide insights into the initial steps in the endosymbiont to organelle transition.
Megan E. S. Sørensen, Mygg L. Stiller, Lena Kröninger, Eva C. M. Nowack   +3 more
wiley   +1 more source

Protocol to fluorescently stain vacuoles in Arabidopsis root cells. [PDF]

STAR Protoc
Tiernan WK, Castro GV, Shipman K, Rodriguez-Furlan C.   +3 more
europepmc   +1 more source

Stress‐inducible phosphoprotein 1 (Sti1/Stip1/Hop) sequesters misfolded proteins during stress

The FEBS Journal, EarlyView.
Stress‐inducible phosphoprotein 1 (Sti1/Stip1/Hop) is a major co‐chaperone to both Hsp90 and Hsp70. We find that misbalanced expression of Sti1 in yeast and mammalian cells causes severe growth defects. Deletion of STI1 causes an accumulation of soluble misfolded ubiquitinated proteins and a strong activation of the heat shock response.
Benjamin S. Rutledge, Young J. Kim, Donovan W. McDonald, Juan C. Jurado‐Coronel, Marco A. M. Prado, Jill L. Johnson, Wing‐Yiu Choy, Martin L. Duennwald   +7 more
wiley   +1 more source

VAPA mediates lipid exchange between Leishmania amazonensis and host macrophages. [PDF]

PLoS Pathog
Gdovinova I, Descoteaux A.
europepmc   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Light at the end of the tunnel: FRAP assays combined with super resolution microscopy confirm the presence of a tubular vacuole network in meristematic plant cells. [PDF]

Plant Cell
Scheuring D, Minina EA, Krueger F, Lupanga U, Krebs M, Schumacher K.   +5 more
europepmc   +1 more source

Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors

The FEBS Journal, EarlyView.
Compounds were identified that inhibit the aspartic protease plasmepsin V from Plasmodium vivax. Further development of these compounds identified compounds, such as S‐WM48, that could inhibit both plasmepsin V and plasmepsin X but plasmepsin IX was not significantly inhibited.
Anthony N. Hodder, Brad E. Sleebs, Greg Adams, Sina Rezazadeh, Anna Ngo, Kate Jarman, Stephen Scally, Peter Czabotar, Hongwu Wang, John A. McCauley, David B. Olsen, Alan F. Cowman   +11 more
wiley   +1 more source