Results 51 to 60 of about 1,407,886 (336)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

COMPARISON OF CONVENTIONAL GAUZE THERAPY WITH VACUUM ASSISTED CLOSURE WOUND THERAPY IN ACUTE TRAUMATIC WOUNDS

open access: yesPakistan Armed Forces Medical Journal, 2013
Objective: To compare the Vacuum Assisted Closure (VAC) wound therapy with Conventional Gauze Therapy (CGT) in management of acute traumatic wounds on the basis of time taken to achieve a vital red wound ready for definitive surgical closure.
Maj Shahid Hussain Naqi   +3 more
doaj   +2 more sources

MODIFIED VAC DRESSING IN STERNAL WOUND INFECTION MANAGEMENT. CHEAP AND FEASIBLE TECHNIQUE IN DEVELOPING COUNTRY

open access: yesFolia Medica Indonesiana, 2017
Sternal wound infection is a rare but serious complication of cardiac surgery leading to prolonged hospital stay and higher mortality. In the last decades several treatment modalities have been described, of which vacuum-assisted closure (VAC) shows the ...
Yan Efrata Sembiring
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Vacuum-assisted closure as alternative method of wound managment

open access: yes, 2022
Vacuum-assisted closure as alternative method of wound ...
Anyshchenko, Anna   +3 more
core   +1 more source

A Novel No Foil-to-Skin Contact Technique for Vacuum-assisted Wound Closure in Patients with Sensitive Skin

open access: yesPlastic and Reconstructive Surgery, Global Open, 2023
Background:. In some patients with chronic wounds, the surrounding skin is so injured due to various underlying conditions that negative pressure dressing cannot be applied or cannot function properly.
Iliyan Emilov Iliev, MD   +3 more
doaj   +1 more source

Improvised vacuum assisted closure dressing for enterocutenous fistula, a case report

open access: yesInternational journal of surgery case reports, 2020
Highlights • Enterocutaneous fistula is a postoperative complication is 75–80% of the cases that results in metabolic complications.• Management of this complication is difficult, necessitating delayed surgery with associated high morbidity and ...
M. Nyamuryekung'e   +3 more
semanticscholar   +1 more source

Traumatic hyphaema following successive vacuum and forceps-assisted delivery [PDF]

open access: yes, 2006
Hyphaema can cause corneal staining and is a potential risk for glaucoma. We report a case of a neonate with isolated traumatic hyphaema following a prolonged delivery with the consecutive use of vacuum and forceps.
Lipton, Jonathan   +2 more
core  

Vacuum assisted closure of wounds – A review

open access: yes, 2010
Background: Vacuum-assisted closure (VAC) therapy is a new technique based on the principle of application of controlled negative pressure. This technique has revolutionized the concept of wound management in recent times.Method: This is a review article
Salati, SAO   +3 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

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