Results 91 to 100 of about 2,799,267 (296)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

Advanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer, Bryan Calder Ackermann, Anna Stoß, Niklas Junker, Ludwig Geisweid, Sabrina Wohlfart, Jonathan Herth, Simon William Pohl, Manuel Ben Böhmann, André Schulz, Victor Aristide Augustin, Gerd Uwe Auffarth, Philipp Uhl   +12 more
wiley   +1 more source

Improvement of surgical treatment for post-ambustial cicatrical deformations using vacuum therapy

Инновационная медицина Кубани, 2019
Background. Improvement of treatment results in patients with cicatrical deformations by means of new surgical techniques and vacuum dressings is the aim of this study.Material and methods.
S. B. Bogdanov, D. N. Marchenko, A. V. Polyakov, A. V. Karakulev, V. A. Aladyina   +4 more
doaj   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

A simple way to deliver vacuum therapy: the tube-in-tube endoluminal vacuum therapy modification [PDF]

Endoscopy, 2020
Marcelo, Lima, Gustavo, Lima, Caterina, Pennacchi, Rodrigo, Scomparin, Gustavo, de Paulo, Bruno, Martins, Fauze, Maluf-Filho   +6 more
openaire   +2 more sources

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source

Vacuum-Assisted wound closure and mesh-mediated fascial traction for open abdomen therapy - a systematic review [PDF]

, 2017
Background: The aim of this paper was to review the literature on vacuum-Assisted wound closure and mesh-mediated fascial traction (VAWCM) in open abdomen therapy. It was designed as systematic review of observational studies.
Björck, Martin, Stefan Acosta, Acosta, Stefan, Petersson, Ulf, Ulf Petersson, Björck, Martin,, Martin Björck   +6 more
core   +1 more source

Quantitative Analysis of Penetrating Wound Behavior Under Vacuum-Assisted Closure Therapy

Medical Devices: Evidence and Research
Tomasz Kossak,1,* Jaroslaw Galkiewicz2,* 1Wojewódzki Szpital Specjalistyczny im. Św. Rafała w Czerwonej Górze, Czerwona Góra, Poland; 2Faculty of Mechatronics and Machine Design, Kielce University of Technology ...
Kossak T, Galkiewicz J
doaj  

Vacuum assisted closure technique: a short review

The Pan African Medical Journal, 2017
The management of difficult to heal wounds has always been a cause of concern for the treating clinicians. There has been a tremendous increase in the number patients presenting with difficult to heal wounds.
Sankalp Yadav, Gautam Rawal, Mudit Baxi
doaj   +1 more source