Results 31 to 40 of about 2,799,267 (296)

Endoscopic Vacuum Therapy for Iatrogenic Rectal Perforation

Case Reports in Gastroenterology, 2022
Serious iatrogenic bowel injuries during screening colonoscopy are rare events. If a perforation is detected during colonoscopy, endoscopic therapy can be attempted depending on the size and type as well as local endoscopic experience. We report the case of a 54-year-old female patient who was treated by endoscopic vacuum therapy (EVT) for a rectal ...
Malte Zumblick, Petros Stathopoulos, Thomas Mathias Gress, Ulrike Walburga Denzer   +3 more
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A pilot study exploring quality of life experienced by patients undergoing negative pressure wound therapy as part of their wound care treatment compared to patients receiving standard wound care [PDF]

, 2014
The use of Negative Pressure Wound Therapy (NPWT) has been widely documented as a technique to help heal complex wounds. This paper presents the findings of a preliminary study which aimed to explore quality of life experienced by patients undergoing ...
Gillibrand, Warren, Stephenson, John, Milne, Jeanette, Gillibrand, Warren P., Cook, Leanne, Ousey, Karen J., Ousey, Karen   +6 more
core   +1 more source

A clinical case of successful application of vacuum therapy in the treatment of postoperative sternomediastinitis

Якутский медицинский журнал
The article presents observation of a clinical case of postoperative sternomediastinitis. The technique of using vacuum therapy in the treatment of purulent wounds is highlighted.
A. A. Shevchenko, E. A. Kashkarov, N. G. Zhila   +2 more
doaj   +1 more source

VACUUM THERAPY IN DIABETIC FOOT SURGERY

Креативная хирургия и онкология, 2017
Introduction. Various techniques of controllable level of negative pressure are presently a trending treatment of purulent-necrotic wounds. Despite the widespread view in the literature about the obvious benefits of this method, there are still no ...
Mazhit A. Nartaylakov, Marat R. Garaev, Vadim D. Dorofeyev, Bulat R. Giniatullin, Vitaliy A. Zavarukhin, Ilshat R. Akhmetshin, Artur K. Burkhanov, Tatyana P. Gvozdik, Rail R. Sharipov   +8 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Massive de-gloving thigh injury treated by vacuum therapy, dermal regeneration matrix and lipografting

African Journal of Paediatric Surgery, 2013
Frequently lower limb injuries are caused by road and work accidents. The young age of those affected coupled with the anatomical and functional peculiarities of this part of the body with regards to social life during adolescence make the treatment of ...
Mario Cherubino, Stefano Scamoni, Igor Pellegatta, Francesca Maggiulli, Anna Minuti, Luigi Valdatta   +5 more
doaj   +1 more source

Modified method of vacuum therapy in the treatment of infected poststernotomy wounds

Бюллетень сибирской медицины, 2020
Sternal wound infections are a terrible complication that require long and complex treatment.The aim of the study was to evaluate the results of using the modified method of vacuum therapy to treat purulentseptic complications of post-sternotomy wounds ...
A. L. Charyshkin, A. A. Guryanov
doaj   +1 more source

Comparative analysis of outcome predictors in patients with postoperative peritonitis depending on the method of surgical treatment – relaparotomy on demand vs vacuum-assisted laparostomy

Инновационная медицина Кубани, 2022
Background: Secondary postoperative diffuse peritonitis (SPDP) is one of the most severe complications of elective and emergency surgical interventions associated with a high mortality rate.
I. B. Uvarov, D. D. Sichinava, A. M. Manuilov   +2 more
doaj   +1 more source