Results 61 to 70 of about 2,799,267 (296)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Vacuum outgassing characteristics of unpigmented 3D printed polymers coated with atomic layer deposited alumina [PDF]

, 2020
Korvaa käsikirjoitus julkaistulla 12 kk:n jälkeen.3-D printing offers enormous potential for fabricating custom equipment for space and vacuum systems, but in order to do this at low-costs, polymers are necessary.
Marin, Giovanni, Pearce, Joshua, Nupur Bihari, Shane Oberloier, Heikkinen, Ismo T.S., Mayville, Pierce J., Maarit Karppinen, Pearce, Joshua M., Joshua M. Pearce, Heikkinen, Ismo T. S., Karppinen, Maarit, Mayville, Pierce, Hele Savin, Giovanni Marin, Oberloier, Shane, Craig Ekstrum, Pierce J. Mayville, Ismo T. S. Heikkinen, Bihari, Nupur, Ekstrum, Craig, Savin, Hele   +20 more
core   +1 more source

VACUUM ASSISTED CLOSURE (VAC) THERAPY FOR DIFFICULT WOUND MANAGEMENT

Pakistan Armed Forces Medical Journal, 2009
Objective: To show the usefulness of vacuum assisted closure (VAC) therapy for management of difficult wounds. Study Design: descriptive type of study.
Usman Ghani, Momin Malik, Zahid Hussain, Javed Ur Rehman, Irfan Shukr   +4 more
doaj  

Current trends in the treatment of intestinal fistulas after combat abdominal injuries

Український журнал клінічної хірургії
Objective. To improve the results of treatment of intestinal fistulas after combat abdominal injuries. Materials and methods. Seventeen wounded patients with intestinal fistulas were examined: type I fistula was found in 6 (35.3%), type II in 4 (23.5%)
O. S. Tyvonchuk, R. I. Vynogradov, I. V. Babii, O. O. Gulenko   +3 more
doaj   +1 more source

Endoscopic vacuum therapy for postoperative esophageal leak [PDF]

BMC Surgery, 2019
Anastomotic leak is the most common and serious complication following esophagectomy. Endoscopic vacuum-assisted closure (EVAC) is a promising method for treating anastomotic leak. We aimed to evaluate the efficacy of EVAC and to identify factors associated with longer treatment duration for esophageal anastomotic leak following esophagectomy for ...
Yang Won Min, Taewan Kim, Hyuk Lee, Byung-Hoon Min, Hong Kwan Kim, Yong Soo Choi, Jun Haeng Lee, Poong-Lyul Rhee, Jae J. Kim, Jae Ill Zo, Young Mog Shim   +10 more
openaire   +3 more sources

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Vacuum tourist plan Canberra 1951 [cartographic material] /

, 1951
Street map of Canberra, Australian Capital Territory, printed in dark green, and overprinted in red, showing places of interest with tourist information.
Vacuum Oil Company.
core  

Up-to-date principles of diagnostics and treatment of chronic wound in diabetic foot patients

Сахарный диабет, 2009
В последние годы отмечен определенный прогресс в лечении больных с синдромом диабетической стопы (СДС). Это обусловлено, в первую очередь, усовер- шенствованием системы длительного наблюдения за больны- ми сахарным диабетом (СД), открытием сети отделений
Alla Yur'evna Tokmakova
doaj   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, EarlyView.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source