Results 161 to 170 of about 27,399 (223)

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham   +19 more
wiley   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady   +5 more
wiley   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins   +3 more
wiley   +1 more source

Highly Tunable and Cell‐Remodelable Thiol‐ene Alginate‐Peptide Crosslinked Hydrogels to Recreate Cellular and Organoid Microenvironments for Biofabrication

open access: yesAdvanced Healthcare Materials, EarlyView.
Norbornene‐functionalized alginate is crosslinked with a di‐thiolated peptide sequence cleavable by cell‐secreted matrix metalloproteinases and decorated with cell‐adhesion peptides upon exposure to UV. Thyroid follicles, endometrial and intestinal organoids are encapsulated in a gentle manner with high cell viability and correct phenotype ...
Julia Fernández‐Pérez   +8 more
wiley   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche   +8 more
wiley   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han   +5 more
wiley   +1 more source

Recombination lasers in the vacuum ultraviolet

AIP Conference Proceedings, 1982
Isoelectronic scaling of known laser transitions to higher ion stages1 has recently been shown to be a useful technique for scaling electron-ion recombination lasers, produced in expanding plasmas, to shorter wave-lengths2. The observation of laser action on a sequence based upon the 4f-5d transition in Ag I (1832 nm), Cd II (537.8 nm) and In III (298 ...
W. T. Silfvast, O. R. Wood
openaire   +1 more source

Repetitive vacuum ultraviolet xenon excimer laser

Review of Scientific Instruments, 1979
A repetitive, tunable, high-power vacuum ultraviolet laser operating on the 172-nm bound–free transition in xenon has been developed for use in photochemistry, selective excitation spectroscopy, and in the generation of coherent radiation in the XUV spectral region. A compact high-voltage generator is employed in conjunction with a coaxial cold-cathode
C B, Edwards   +3 more
openaire   +2 more sources

Vacuum-ultraviolet laser-excited spectra of Xe_2

Optics Letters, 1984
Fluorescence excitation of Xe(2) at 149.0 nm has been observed using a pulsed supersonic jet for dimer formation and cooling and using tunable coherent VUV radiation from four-wave mixing in Mg vapor for excitation. The resolved vibronic structure resulting from isotopic Xe(2) molecules has yielded unambiguous vibrational numbering (upsilon'=37-46 ...
R H, Lipson   +2 more
openaire   +2 more sources

Vacuum ultraviolet laser spectra of ICl

The Journal of Chemical Physics, 1989
Vacuum ultraviolet fluorescence excitation spectra of jet cooled ICl have been recorded between 158 and 166 nm using a VUV ‘‘laser’’ generated by four-wave sum-mixing in Mg vapor. An unambiguous vibrational analysis of the spectra has shown that transitions from v″=0 of the ground state probe high vibrational levels of the first tier EO+ ion-pair state
R. H. Lipson, A. R. Hoy
openaire   +1 more source

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