Results 61 to 70 of about 130,167 (293)
Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
Imaging of Canine Neoplastic Reproductive Disorders
Animals, 2021 Diagnostic imaging plays an essential role in the diagnosis and management of reproductive neoplasia in dogs and cats. The initial diagnosis, staging, and planning of surgical and radiation treatment and the response to therapy all involve imaging to ...
Marco Russo +3 more
doaj +1 more source
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Journal of the American Medical Association, 1912 Tumors of the vagina are comparatively infrequent. New growths of all varieties, however, both cystic and solid, occasionally originate in the structures of this organ. Cystic Cystic tumors form a goodly percentage of all vaginal growths, although they are not common.
openaire +2 more sources
An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management
Advanced Science, EarlyView.Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer +12 more
wiley +1 more source
SAV1 in Cooperation With FKBP52 Participates in Implantation
Advanced Science, EarlyView.The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao +10 more
wiley +1 more source
CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs
Advanced Science, EarlyView.In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang +16 more
wiley +1 more source
Tabique vaginal longitudinal aislado: a propósito de un caso
Medicentro, 2016 Las anomalías estructurales del aparato reproductor femenino se manifiestan en diferentes momentos cronológicos: desde el nacimiento, la niñez, la pubertad, durante la menarca en la adolescencia o en las etapas posteriores de la vida.El aparato ...
Nuria Vega Betancourt +2 more
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