Results 91 to 100 of about 1,388,671 (213)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomized controlled trial.

, 2010
BACKGROUND: Herpes simplex virus (HSV) suppressive therapy reduces genital and plasma human immunodeficiency virus type 1 (HIV-1) RNA over periods up to 3 months, but the long-term effect is unknown.
Mugeye, Kokugonza, Changalucha, John, Weiss, Helen A, Watson-Jones, Deborah, Tanton, Clare, Hayes, Richard J, Baisley, Kathy, Clayton, Tim C, Rusizoka, Mary, Ross, David A, Everett, Dean, Legoff, Jerome, Belec, Laurent   +12 more
core   +1 more source

Circular Economy in the Healthcare Industry: Developing a Circularity Assessment Tool for Complex Medical Devices

Business Strategy and the Environment, EarlyView.
ABSTRACT As the circular economy transition gains traction in the healthcare sector, extending the lifespan of complex medical devices has become a key priority, given their high cost and the challenges associated with their technological sophistication.
Tetiana Shevchenko, Lauren Durivault, Meisam Ranjbari, Zahra Shams Esfandabadi, Bernard Yannou, Robert Heidsieck, Michael Saidani, Ghada Bouillass   +7 more
wiley   +1 more source

Decreased neonatal pain response after vaginal-operative delivery with Kiwi OmniCup versus metal ventouse [PDF]

, 2017
Background Vaginal delivery, especially operative assisted vaginal delivery, seems to be a major stressor for the neonate. The objective of this study was to evaluate the stress response after metal cup versus Kiwi Omnicup® ventouse delivery. Methods The
S. von Felten, Visca, E, von Felten, S, Zimmermann, R, D. R. Vogt, Tinner Oehler, Eva Maria Eugenia, Vogt, D R, Hoesli, I, E. A. Huhn, Surbek, Daniel, E. Visca, Bührer, C, Oehler, E. M. Tinner, Zimmermann, R., R. Zimmermann, I. Hoesli, Vogt, D. R., Surbek, D., C. Bührer, E. M. Tinner Oehler, von Felten, S., Buehrer, C., Visca, E., D. Surbek, Huhn, E. A., Huhn, E A   +25 more
core   +2 more sources

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian, Floriane Jochum, Elise Dumas, Florence Coussy, Kevin Bihan, Bénédicte Lebrun‐Vignes, Barbara Pistilli, Marc‐Antoine Benderra, Lise Selleret, Laurent Chouchana, Fabien Reyal, Anne‐Sophie Hamy, Paul Gougis   +12 more
wiley   +1 more source

Outcomes in term breech birth according to intended mode of delivery—A Swedish prospective single‐center experience of a dedicated breech birth team

Acta Obstetricia et Gynecologica Scandinavica
Introduction The appropriate mode of delivery for breech babies is a topic of ongoing debate. After the publication of the Term Breech Trial in 2000, the proportion of breech babies delivered vaginally in Sweden rapidly dropped to 7% from 26%.
Nicolas Yaouzis Olsson, Emma Debora Bartfai, Hanna Åmark, Tove Wallström   +3 more
doaj   +1 more source

Three‐dimensional observation of the muscle–tendon integration process in mouse embryos

Developmental Dynamics, EarlyView.
Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki, Anzu Taniguchi, Shunsuke Oka, Mizuki Mishima, Yuki Yamasaki, Yutaro Kawa, Saundra Schlesinger, Ryo Fujita, Chisa Shukunami, Hiroshi Asahara, Masafumi Inui   +10 more
wiley   +1 more source

Failed operative vaginal delivery

, 2009
To compare maternal and neonatal outcomes in women undergoing second-stage cesarean delivery after a trial of operative vaginal delivery with those in women undergoing second-stage cesarean delivery without such an attempt.
Miodovnik, Menachem, Langer, Oded, Varner, Michael W, Sibai, Baha M, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal–Fetal Medicine Units Network (MFMU), Gilbert, Sharon, Gabbe, Steven G, Spong, Catherine Y, Sorokin, Yoram, O'Sullivan, Mary J, Alexander, James M, Wapner, Ronald J, Meis, Paul, Caritis, Steve N, Hauth, John C, Leveno, Kenneth J, Landon, Mark B   +16 more
core   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Freeze-dried cylinders carrying chitosan nanoparticles for vaginal peptide delivery

, 2017
Recently nanoparticle-based vaginal drug delivery formulations have been acquiring great attention for the administration of peptide based-vaccines or microbicides to prevent or treat sexually transmitted diseases.
Silvia Rossi, Remuñán-López, Carmen, ROSSI, SILVIA STEFANIA, Caramella, Carla, Carla Caramella, Remunan Lopez, Carmen, Carmen Remuñán-López, Rossi, Silvia, CARAMELLA, CARLA MARCELLA, Marciello, Marzia, Marzia Marciello   +10 more
core   +1 more source