Results 41 to 50 of about 1,388,671 (213)

Mode of delivery and maternal outcome in subsequent delivery after an obstetric anal sphincter injury: a Finnish retrospective cohort study

BMC Pregnancy and Childbirth
Background Obstetric anal sphincter injury (OASI) is a severe complication of vaginal delivery. In previous studies, parturients with a preceding OASI are at increased risk of a recurrent OASI (rOASI) in subsequent vaginal deliveries.
Elina Ristilä, Outi Palomäki, Heini Huhtala, Elli Toivonen   +3 more
doaj   +1 more source

An assessment of the likely acceptability of vaginal microbicides for HIV prevention among women in rural Ghana. [PDF]

, 2012
BACKGROUND: The findings of the CAPRISA tenofovir studies have raised expectations that soon an approved microbicide would be available. However it is in only a limited number of countries in sub-Saharan Africa that the acceptability of microbicides has ...
Tawiah, Charlotte, Charlotte Tawiah, Frank Baiden, Afari-Asiedu Samuel, Martha A Abdulai, Afari-Asiedu, Samuel, Abdulai, Martha A, Abdulai Martha A, Adjei Kwame, Baiden, Frank, Baiden Frank, Samuel Afari-Asiedu, Sam Newton, Adjei, George, Adjei George, Adjei, Kwame, Newton Sam, George Adjei, Tawiah Charlotte, Newton, Sam, Kwame Adjei   +20 more
core   +2 more sources

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Postpartum Hemorrhage Following Vaginal and Cesarean Section Deliveries at a Single Tertiary Hospital: A Five-year Cross-sectional Study

Oman Medical Journal
Objectives: This study aimed to examine the prevalence, etiology, management, and outcomes of postpartum hemorrhage (PPH) following vaginal and cesarean delivery.
Miriam George Fenn, Maisa Al Falahi, Taif Al Hannai, Lubna Al Shukaili, Nihal Al Riyami   +4 more
doaj   +1 more source

The association of maternal obesity and obstetric anal sphincter injuries at time of vaginal deliveryAJOG Global Reports at a Glance

AJOG Global Reports, 2023
BACKGROUND: The risk of third- and fourth-degree perineal laceration after vaginal delivery in patients with obesity is relatively understudied and has mixed findings in existing literature.
Amin Tavakoli, MD, Viraj R. Panchal, MD, Genevieve R. Mazza, MD, Rachel S. Mandelbaum, MD, Joseph G. Ouzounian, MD, MBA, Koji Matsuo, MD, PhD   +5 more
doaj   +1 more source

Are women who work in bars, guesthouses and similar facilities a suitable study population for vaginal microbicide trials in Africa? [PDF]

, 2010
BACKGROUND: A feasibility study was conducted to investigate whether an occupational at-risk cohort of women in Mwanza, Tanzania are a suitable study population for future phase III vaginal microbicide trials.
Suzanna C. Francis, Stella Kasindi, Watson-Jones Deborah, Shagi, Charles, Claire Cook, Francis, Suzanna C, Watson-Jones, Deborah, Tobias Chirwa, Cook, Claire, Richard J. Hayes, Suzanna C Francis, Microbicides Development Programme, Louise Knight, Vallely Andrew, Celia Barberousse, Hayes, Richard J, Deborah Watson-Jones, Francis Suzanna C., Knight, Louise, Ross, David, Ian R Hambleton, Changalucha John, Everett Dean, Everett, Dean, Hambleton Ian R., Vallely, Andrew, Charles Shagi, Cook Claire, Changalucha, John, Shagi Charles, Hambleton, Ian R, Chirwa, Tobias, John Changalucha, Barberousse Celia, Kasindi Stella, Knight Louise, Dean Everett, Richard J Hayes, null null, Kasindi, Stella, Barberousse, Celia, Ian R. Hambleton, Ross David, Chirwa Tobias, Andrew Vallely, David Ross, Hayes Richard J.   +46 more
core   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

A Comparison of Dequalinium Chloride Vaginal Tablets (Fluomizin (R)) and Clindamycin Vaginal Cream in the Treatment of Bacterial Vaginosis: A Single-Blind, Randomized Clinical Trial of Efficacy and Safety [PDF]

, 2012
Aims: To investigate if vaginal application of dequalinium chloride (DQC, Fluomizin (R)) is as effective as vaginal clindamycin (CLM) in the treatment of bacterial vaginosis (BV).
Gerber, Stefan, Spacek, Jiri, Unzeitig, Vit, Weissenbacher, Ernst Rainer, de Tejada, Begona Martinez, Halaska, Michael, Donders, Gilbert, Martinez De Tejada Weber, Begona, Unzeitig, V., Špaček, J., Martinez de Tejada, B., Halaška, M., Gerber, S., Weissenbacher, E.R., Donders, G.   +14 more
core   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source