Results 131 to 140 of about 237,239 (331)

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts   +7 more
wiley   +1 more source

Learning with Patient Campaigners About a German Drug Scandal

open access: yesBerichte zur Wissenschaftsgeschichte, EarlyView.
The West German drug Duogynon is internationally marketed as a “hormone pregnancy test” (HPT) between the 1950s and 1980s. In the late 1960s, it comes under suspicion for inducing miscarriage, spina bifida, and a spectrum of birth defects similar to those caused by the sedative thalidomide.
Jesse Olszynko‐Gryn   +3 more
wiley   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

open access: yesBMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang   +6 more
wiley   +1 more source

The state of vaginal microbiocenosis of adolescent girls with urinary tract and gastrointestinal diseases

open access: yesActa Biomedica Scientifica
Justification. Changes in the microbiocenosis of the vagina of adolescent girls with diseases of the urinary tract and gastrointestinal tract may be a marker of future diseases of the reproductive system.
M. Yu. Akhmetova   +4 more
doaj   +1 more source

Estimating resource needs for HIV/AIDS health care services in low-income and middle-income countries.

open access: yes, 2004
As funding mechanisms like the Global Fund for HIV/AIDS, Tuberculosis and Malaria increasingly make funding decisions on the basis of burden of disease estimates and financial need calculations, the importance of reliable and comparable estimating ...
Bertozzi, Stefano   +4 more
core   +1 more source

Autonomic Plexuses of the Female Sexual Organs Travel Within Pubocervical and Rectovaginal [Endopelvic] Fascia: A Rationale for ‘Nerve‐Aware’ Vaginal Prolapse Repair

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The connective tissue support of female pelvic viscera—endopelvic fascia—has been studied in fetal and immunohistochemical models to demonstrate its relationship with the autonomic nerves of the female pelvis. Due to a paucity of literature examining the gross anatomical relationships between endopelvic fascia and autonomic nerves in adult ...
Stephen Magliocchetti   +5 more
wiley   +1 more source

Progress in prevention of mother-to-child transmission of HIV infection in Ukraine: results from a birth cohort study [PDF]

open access: yes, 2009
Background: Ukraine was the epicentre of the HIV epidemic in Eastern Europe, which has the most rapidly accelerating HIV epidemic world-wide today; national HIV prevalence is currently estimated at 1.6%.
Malyuta, R   +4 more
core  

Synthesis of an Enzyme‐Triggered Chitosan‐Based Drug Delivery System for Peri‐Implantitis Prevention

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Dental implants have become a leading solution for tooth loss, yet bacterial infections remain a major complication. Antibacterial implant coatings are an important approach to reduce or prevent bacterial infections at the implant. Given the oral cavity's complex microbiome and the importance of some commensal bacteria, it is crucial to ...
Nelly Senze Nnane   +7 more
wiley   +1 more source

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