Results 131 to 140 of about 10,779,854 (376)

Refining Domain‐Based Prognostication in DNM1 Encephalopathy: A Mild Phenotype Associated With a GTPase Domain Variant

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT DNM1 encephalopathy is a rare autosomal dominant genetic condition characterized by a range of neurological and developmental manifestations. The typical phenotype is severe, including profound intellectual disability, treatment‐resistant epilepsy, ataxia, and structural brain abnormalities. However, milder presentations have increasingly been
Caroline Crain   +6 more
wiley   +1 more source

Determinants of bacterial vaginosis (BV) in HIV negative women living in Cape Town, South Africa : a cross-sectional study

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 55-60).Bacterial vaginosis (BV) is a common cause of vaginal symptoms among women of childbearing age, although some women may be asymptomatic.
Gopolang, Felicity Pinkie
core  

Spray-dried powders enhance vaginal siRNA delivery by potentially modulating the mucus molecular sieve structure

open access: yes, 2015
Na Wu,1,2,* Xinxin Zhang,2,* Feifei Li,2 Tao Zhang,2 Yong Gan,2 Juan Li1 1School of Pharmacy, China Pharmaceutical University, Nanjing, People’s Republic of China; 2Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai ...
Zhang XX   +11 more
core   +1 more source

Vaginal microbiota transplantation for the treatment of vaginal dysbiosis and bacterial vaginosis: A scoping review

open access: yes, 2023
Vaginal dysbiosis and bacterial vaginosis have significantly impacted women’s physical health, quality of life, and psychological well-being. However, the traditional antibiotic treatment often fail to completely cure diseases, frequently leading to ...
Luohaiqin
core   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu   +6 more
wiley   +1 more source

Understanding and Preventing Recurring Bacterial Vaginosis: Important Considerations for Clinicians

open access: yesInternational Journal of Women's Health, 2023
Christina A Muzny,1 Jack D Sobel2 1Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 2Division of Infectious Diseases, Department of Medicine, Wayne State University, Detroit, MI ...
Muzny CA, Sobel JD
doaj  

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang   +7 more
wiley   +1 more source

HPV and HPV-associated cervical diseases in women, who use hormonal methods of contraception: diagnostic and treatment management of abnormal cytology test result

open access: yesМедицинский совет, 2019
If abnormal cytology test results are identified in the users of hormonal methods of contraception, including a vaginal ring, they should adhere to diagnostic algorithms aimed at identifying and treating HPV-associated cervical diseases. NovaRing vaginal
N. M. Nazarova   +2 more
doaj   +1 more source

Canine brachycephalic obstructive airway syndrome as a model for studying the effects of obstructive sleep apnea during pregnancy

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We observed a negative effect of brachycephalic obstructive airway syndrome (BOAS) in a staggered manner based on the severity of the condition on respiratory and cardiac patterns, glycemia, acid–base balance, fetal growth, and uterine artery hemodynamics, thus requiring adaptations within the fetal–placental unit. Severely affected bitches had uterine
Roberto Rodrigues da Rosa Filho   +4 more
wiley   +1 more source

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