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Vaginal Intraepithelial Neoplasia

Journal of Lower Genital Tract Disease, 2016
Vaginal squamous intraepithelial neoplasia (VaIN) is uncommon when comparing to the cervical or vulval counterparts. Almost all are caused by infection of human papillomaviruses (HPVs). Traditionally, VaIN was classified into grades I, II, and III, depending on the degree of involvement of the epithelium by the dysplastic cells.
Ip, PPC, Tse, KY
core   +8 more sources

Systemic adverse events in imiquimod use for cervical intraepithelial neoplasia – A case series [PDF]

Case Reports in Women's Health, 2019
Treatment for cervical intraepithelial neoplasia (CIN) often consists of an excisional procedure. However, less invasive treatment methods have been explored, such as topical treatment with imiquimod cream.
Tirza Wouters, Natasja Hendriks, Margot Koeneman, Arnold-Jan Kruse, Anna van de Sande, Heleen J. van Beekhuizen, Kees G. Gerestein, Ruud L.M. Bekkers, Jurgen M.J. Piek   +8 more
doaj   +2 more sources

Economic burden of vulvar and vaginal intraepithelial neoplasia: retrospective cost study at a German dysplasia centre [PDF]

BMC Infectious Diseases, 2011
Background Human papillomavirus is responsible for a variety of diseases including grade 2 and 3 vulvar and vaginal intraepithelial neoplasia. The aim of this study was to assess parts of the burden of the last diseases including treatment costs.
Kok Patrick, Schulz-Holstege Olaf, Huppertz Eduard, Hampl Monika, Schmitter Sarah   +4 more
doaj   +3 more sources

Imiquimod for treatment of vulvar and vaginal intraepithelial neoplasia

International Journal of Gynecology & Obstetrics, 2008
We searched PubMed, Scopus, Web of Science, LILACS, EMBASE, and Cochrane Library databases to assess the effectiveness and safety of 5% imiquimod cream in the treatment of vulvar and vaginal intraepithelial neoplasia. From the results of the 17 relevant articles identified (1 reported on a randomized controlled trial, 10 reported on case series, and 6 ...
Lavazzo, Christos, Pitsouni, Eleni, Athanasiou, Stavros, Falagas, Matthew E.   +3 more
core   +5 more sources

Detection of Human Papillomavirus Infection in Patients with Vaginal Intraepithelial Neoplasia. [PDF]

PLoS ONE, 2016
Vaginal intraepithelial neoplasia (VAIN) is a pre-malignant lesion, potentially leading to vaginal cancer. It is a rare disease, representing less than 1% of all intraepithelial neoplasia of the female genital tract.
Cristina Lamos, Charlotte Mihaljevic, Sebastian Aulmann, Thomas Bruckner, Christoph Domschke, Markus Wallwiener, Carmen Paringer, Herbert Fluhr, Sarah Schott, Christine Dinkic, Janina Brucker, Michael Golatta, Lisa Gensthaler, Michael Eichbaum, Christof Sohn, Joachim Rom   +15 more
doaj   +2 more sources

Proximal Partial Vaginectomy for Vaginal Intraepithelial Neoplasia. [PDF]

J Obstet Gynaecol India, 2019
The purpose of this study was to evaluate the use of proximal partial vaginectomy for the treatment of VaIN.Descriptive.Between May 2009 and December 2017, 20 patients were identified who underwent partial vaginectomy for VaIN. The electronic medical records were reviewed and information collated.A circular incision in mid-vagina, was taken for all ...
Bhati P, Samynathan K, Sebastian A, Thomas A, Chandy R, Peedicayil A.   +5 more
europepmc   +4 more sources

Clinical characteristics and risk factors to high-grade vaginal intraepithelial neoplasia: a single-institution study [PDF]

BMC Women's Health
Background To date, few studies have investigated the factors associated with high-grade vaginal intraepithelial neoplasia (VaIN). This study aimed to analyze the characteristics of high‐grade VaIN and identify its underlying risk factors.
Min Lu, Xiaoshan Hong, Tingyan Liu, Bi Mai, Guiying Hu, Xiaoli Sun   +5 more
doaj   +2 more sources

Cytology and HPV Co-Testing for Detection of Vaginal Intraepithelial Neoplasia: A Retrospective Study. [PDF]

Cancers (Basel), 2023
(1) Background: Vaginal intraepithelial neoplasia (VaIN) is a rare premalignant disease caused by persistent human papillomavirus (HPV) infection. Diagnosing VaIN is challenging; abnormal cytology and positive HPV tests are usually the first signs, but ...
Stuebs FA, Dietl AK, Koch MC, Adler W, Geppert CI, Hartmann A, Knöll A, Mehlhorn G, Beckmann MW, Schulmeyer CE, Heindl F, Emons J, Seibold A, Behrens AS, Gass P.   +14 more
europepmc   +2 more sources

Risk of prostate cancer after isolated high-grade prostatic intraepithelial neoplasia (HGPIN) detected on extended core needle biopsy : a UK hospital experience. [PDF]

, 2009
Background High-grade prostatic intraepithelial neoplasia (HGPIN) is a precursor lesion to prostate cancer (CaP). UK-based studies examining the occurrence of isolated HGPIN and subsequent risk of CaP are lacking.
Singh, Paras B., Nicholson, Caroline M., Blades, Rosemary A., Matanhelia, Shyam S., Ragavan, Narasimhan, Martin, Frank L.   +5 more
core   +6 more sources

Successful endoscopic treatment for high-grade cervical intraepithelial neoplasia with gross lesions of the vagina

Gynecology and Minimally Invasive Therapy, 2021
We present a patient diagnosed with high-grade cervical intraepithelial neoplasia (CIN) combined with macroscopic lesions of the vaginal epithelium. There was no lesion in pelvic magnetic resonance imaging examination, and histopathological examination ...
Koyo Yamamoto, Miho Kitai, Kasumi Yamamoto, Toshiko Sakuma, Shoji Nagao, Satoshi Yamaguchi   +5 more
doaj   +1 more source