Results 91 to 100 of about 8,495 (212)

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Periodontal diseases and adverse pregnancy outcomes. Present and future

Periodontology 2000, EarlyView., 2023
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis, Mark Ide, Mervi Gürsoy, Phoebus N. Madianos   +3 more
wiley   +1 more source

Optical Coherence Tomography Angiography in the Assessment of Vulvar Lichen Sclerosus Vascularity and Epithelial Thickness In Vivo

Translational Biophotonics, EarlyView.
Optical Coherence Tomography Angiography in the Assessment of Vulvar Lichen Sclerosus ABSTRACT Vulvar lichen sclerosus is a chronic inflammatory skin condition that leads to scarring and an increased risk of squamous cell carcinoma. It presents clinically as atrophic white patches or plaques, often with associated fissures, erosions, hyperkeratosis ...
Raksha Sreeramachandra Murthy, Christina N. Kraus, Felicia Lane, Zhongping Chen   +3 more
wiley   +1 more source

Imaging in gynecological disease (28): clinical and ultrasound characteristics of serous and mucinous cystadenomas in the adnexa

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To describe the clinical and ultrasound characteristics of serous and mucinous cystadenomas in the adnexa. Methods This was a retrospective international multicenter study. Using the International Ovarian Tumor Analysis (IOTA) database, patients with a histological diagnosis of serous or mucinous cystadenoma who had undergone ...
F. Mascilini, F. Moro, T. Pasciuto, P. Sladkevicius, W. Froyman, L. Jokubkiene, C. Van Holsbeke, D. Franchi, E. Epstein, S. Guerriero, V. Chiappa, F. Buonomo, M. J. Kudla, J. L. Alcázar, L. Hochberg, F. Ciccarone, L. Quagliozzi, G. Scambia, D. Timmerman, L. Valentin, A. C. Testa   +20 more
wiley   +1 more source

Emerging trends in the management of non‐obstructive azoospermia

UroPrecision, EarlyView.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad, Mohamed Alkabeer, Dina Abdelmonim, Sameh Fayek GamalElDin, Mohamed Wael Ragab   +4 more
wiley   +1 more source

Isolated asthenozoospermia: What should we know? A narrative review of literature

UroPrecision, EarlyView.
ABSTRACT Male infertility contributes to 20%–70% of infertile couple cases worldwide. One of the key challenges in this area is asthenozoospermia or reduced sperm motility. A particular subset, known as isolated asthenozoospermia (iASZ), in which low motility occurs without abnormalities in sperm count or shape, often goes unnoticed and is not well ...
Ahmed Eissa, Khaled Almekaty, Ahmed Zoeir, Hussein Mamdoh, Ayman Mousa, Mohammed Abou‐elenein, Tarek Gameel, Maged Ragab   +7 more
wiley   +1 more source

Kussmaul's Sign Provoked by Intracardiac Metastasis of Endometrial Neuroendocrine Tumor

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yi‐Hsun Chen, Chin‐Chuan Chang, Yao‐Kuang Wang, I‐Chen Wu   +3 more
wiley   +1 more source

Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen

VIEW, EarlyView.
We summarize the taxonomic characteristics, capabilities to adhere to and invade host cells, extra‐oral ectopic colonization pathways, and major pathogenic mechanisms of Fusobacterium nucleatum, and explore the regulation of F. nucleatum’s pathogenesis, aiming to provide references and assistance for the development of clinical interventions and future
Zhiwei Guan, Houbao Qi, Qiang Feng
wiley   +1 more source

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

VIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou, Qiancheng Mao, Junpeng Chi, Jiankun Zhang, Hao Guo, Jitao Wu, Yuanshan Cui   +6 more
wiley   +1 more source

Maternal Immune Activation During Pregnancy and Obstetric Outcomes: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Maternal immune activation has been proposed as a mechanism for adverse pregnancy outcomes, yet the mechanisms and effects of timing remain unclear. Immune disruption in early gestation may be particularly detrimental as this is an important period for placental development, which has been associated with the pathology of adverse ...
Frederieke A. J. Gigase, Myrthe M. G. B. M. Boekhorst, Anna Suleri, Anna‐Sophie Rommel, Michael Breen, Ryan L. Muetzel, Manon H. J. Hillegers, Michal A. Elovitz, Eric A. P. Steegers, Lot D. De Witte, Veerle Bergink   +10 more
wiley   +1 more source