Results 111 to 120 of about 8,495 (212)

Long‐term quality of life, vulvar symptoms, and sexual functioning: A cross‐sectional study of Norwegian vulvar cancer survivors

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
A considerable proportion of vulvar cancer survivors experienced persistent functional impairments, even more than 5 years posttreatment. Additionally, they reported more vulvar symptoms and sexual dysfunction compared to women from a normative population sample.
Christin Julia Meltzer‐Gunnes   +4 more
wiley   +1 more source

Pelvic organ‐sparing robot‐assisted radical cystectomy in women with bladder cancer

open access: yesBJU International, EarlyView.
Objectives To investigate the oncological and complication outcomes in women who have undergone pelvic organ‐sparing robot‐assisted radical cystectomy (RARC). Patients and Methods We conducted a retrospective, multicentre cohort study of women with bladder cancer undergoing RARC with intracorporeal urinary diversion.
Juhana Rautiola   +11 more
wiley   +1 more source

Susceptibility of Brca1(L63X/+) rat to ovarian reserve dissipation by chemotherapeutic agents to breast cancer

open access: yesCancer Science, Volume 116, Issue 4, Page 1139-1152, April 2025.
We analyzed the effects of olaparib in the presence and absence of cyclophosphamide in a recently established rat BRCA1‐mutant model and found for the first time that mutant ovaries are more susceptible to oxidative stress, potentially depleting primordial follicles via activation of granulosa cells and inducing oocyte death due to accumulated DNA ...
Satoshi Kaseki   +10 more
wiley   +1 more source

Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA–RNA Comprehensive Genomic Profiling Test

open access: yesCancer Science, EarlyView.
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe   +7 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Re: Nonmelanomatous Skin Cancer Following Cervical, Vaginal, and Vulvar Neoplasms: Etiologic Association   RESPONSE [PDF]

open access: yesJNCI Journal of the National Cancer Institute, 1999
Frisch, M.   +4 more
openaire   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

Neurodevelopmental outcome of perinatal intracranial haemorrhage in patients born at term: A prospective study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To assess the neurological and neurodevelopmental outcome of infants born at term with perinatal intracranial haemorrhage (pICH) and examine the clinical and neuroimaging associations. Method A prospective, consecutive, single‐center observational study of longitudinally followed children with pICH identified in the fetal or neonatal ...
Stephanie Libzon   +9 more
wiley   +1 more source

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