Results 151 to 160 of about 8,495 (212)

Radical cystectomy mortality in older patients: a systematic review and meta‐analysis

BJU International, Volume 136, Issue 1, Page 19-31, July 2025.
Objective To perform a systematic review and meta‐analysis of post‐radical cystectomy (RC) mortality and complications in older people to aid decision‐making pertinent to RC, as bladder cancer is typically a disease of older people, yet older people are less likely than their younger peers to undergo RC, predominantly due to concerns about morbidity ...
Jake Tempo, Sulleyman Felemban, Kirby R. Qin, Marlon Perera, Joseph Ischia, Damien Bolton, Declan G. Murphy, Brian Kelly, David I. Watson, Michael O’Callaghan   +9 more
wiley   +1 more source

p16/ki‐67 dual stain triage of individuals positive for HPV to detect cervical precancerous lesions

International Journal of Cancer, Volume 156, Issue 12, Page 2257-2264, 15 June 2025.
Abstract p16/Ki‐67 dual stain is a biomarker‐based test that can identify oncogenic transformation in cervical cells with higher sensitivity than cervical cytology, using the same samples taken for human papillomavirus (HPV) testing and liquid‐based cytology.
Diane M. Harper, Tamera Paczos, Ruediger Ridder, Warner K. Huh   +3 more
wiley   +1 more source

501 Vaginectomy as Treatment of Isolated Vaginal Relapse (IVR) of Gynecological Neoplasms

International Journal of Gynecological Cancer, 2004
N. Manci, R. Angioli, L. Muzii, M.A. Zullo, F. Bellati, C.L. De Falco, S. Basile, G. Perniola, P. Benedetti Panici   +8 more
openaire   +1 more source

Long Noncoding RNA NONHSAT233728.1 Promotes ROS Accumulation and Granulosa Cell Apoptosis by Regulating the MAPK/ERK1/2 Signaling Pathway

The FASEB Journal, Volume 39, Issue 11, 15 June 2025.
Through isolation and transcriptomic profiling of granulosa cells, we identified the functional significance of lncRNA NONHSAT233728.1 in polycystic ovary syndrome (PCOS) pathogenesis. Knockdown of lncRNA NONHSAT233728.1 in granulosa cells elevated ROS levels, reduced the Bcl2/Bax ratio, downregulated phospho‐ERK1/2, and increased IL‐8 secretion. These
Yao Chen, Heqi Dai, Fei Mao, Yangbai Li, Ruizhi Feng, Yun Qian   +5 more
wiley   +1 more source

Topics of Interest in Women With Myeloproliferative Neoplasms

American Journal of Hematology, Volume 100, Issue S4, Page 74-87, June 2025.
Women with MPN: life‐cycle phases, specific risks, and influencing factors. ABSTRACT Overview Sex and gender have emerged as central modifiers of disease biology, phenotype, and clinical outcomes in myeloproliferative neoplasms (MPNs). This review will uniquely highlight issues affecting women with MPN and articulate their relevant determinants ...
Natasha Szuber, Paola Guglielmelli, Naseema Gangat   +2 more
wiley   +1 more source

Giant Bladder Diverticulum in A Female Infant Mimicking Intraperitoneal Mass

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Urinary bladder diverticula can be either primary (congenital) or secondary (acquired) and are more commonly observed in males, sometimes in association with syndromes. The condition presents with a wide range of symptoms, while some cases may remain asymptomatic.
Jay Lodhia, Mujaheed Suleman, Samwel Chugulu, Kondo Chilonga, David Msuya   +4 more
wiley   +1 more source

A Rare Case of Four Primary Tumors in a Patient With Lynch Syndrome

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT This case emphasizes the complexity of LS and the need for more comprehensive surveillance strategies, particularly in those with MPTs, to enable early detection and improve management.
Mostafa Kamandi, Negin Layegh, Hamideh Feiz Disfani   +2 more
wiley   +1 more source

Vulvar Adenocarcinoma With Pagetoid Spread: A Case Report

Cancer Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Background In rare cases, cancer cells adjacent to the skin migrate intraepithelially and reach the epidermis, presenting a histological appearance similar to that of Paget's disease; this phenomenon is termed pagetoid spread. Herein, we report a case of vulvar adenocarcinoma with pagetoid spread, in which the primary lesion could not be ...
Kazuaki Nishimura, Seiji Kagami, Haruka Kajio, Tamaki Wada, Naoyuki Toki, Kiyoshi Yoshino   +5 more
wiley   +1 more source

Changes of Microbiome in Human Papillomavirus Infection and Cervical Cancer: A Systematic Review and Meta‐Analysis

Cancer Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Background and Objectives We aimed to conduct a systematic review and meta‐analysis of high‐throughput sequencing studies to assess changes in microbiome alpha, beta diversity, and composition differences in patients with human papillomavirus (HPV) infection and cervical cancer.
Wei Zhang, Yan Ge, Lihe Yao, Qingchun Yan, Jiuju Wei, Yanfei Yin, Bin Liu   +6 more
wiley   +1 more source

The Value of P16 Protein Detection in the Screening for High‐Grade Squamous Intraepithelial and Higher Lesions of the Cervix by the Combined Detection of HR‐HPV and TCT

Diagnostic Cytopathology, Volume 53, Issue 6, Page 283-289, June 2025.
ABSTRACT Liquid‐based thin layer cytology (TCT) and HR‐HPV detection are the most important screening methods for cervical cancer. These two methods have limited sensitivity and specificity, so some cervical lesions are still missed or misdiagnosed. This paper mainly discusses the value of P16 protein detection in cervical cancer screening.
Jiayu Zhou, Mi Tang, Chunhua Lin, Wei Chen   +3 more
wiley   +1 more source