Results 181 to 190 of about 32,918 (328)

Clinical value of high‐frequency ultrasound and serum miR‐92a‐3p in diabetic peripheral neuropathy

open access: yesJournal of Diabetes Investigation, EarlyView.
Serum miR‐92a‐3p and CSAs of median, ulnar, and tibial nerves are elevated in DPN patients. Their combination has high diagnostic significance in identifying DPN in T2DM patients and assessing its severity. ABSTRACT Aims/Introduction Cross‐sectional area (CSA) by high‐frequency ultrasound (HF‐US) detects morphologic changes in neuropathy. microRNA (miR)
Chunmei Qiao   +6 more
wiley   +1 more source

Increase of astrocyte apposition on GnRH neurons in early puberty onset induced by high fat diet

open access: yesJournal of Neuroendocrinology, EarlyView.
This study suggests that the HFD‐induced anticipation of puberty seems to be, at least partially, mediated by an increase in the interaction between astrocytes and GnRH neurons in both the MPOA and ARC/EM, which may increase the excitability of GnRH neurons.
Isabelle Rodrigues‐Santos   +8 more
wiley   +1 more source

Maternal high fat and high sugar diet impacts on key DNA methylation enzymes in offspring brain in a sex‐specific manner

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Maternal obesity associates with an increased risk of offspring neurodevelopmental disorders. Although the underlying mechanism(s) remain unclear, evidence suggests a role for altered DNA methylation. We utilized a murine model of diet‐induced obesity to investigate the impact of maternal obesity on the offspring brain transcriptome and DNA ...
Kahyee Hor   +5 more
wiley   +1 more source

Dynamic changes in Ccn3 expression across the limbic forebrain through the mouse estrous cycle and during lactation

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Cellular communication network factor 3 (CCN3), also known as nephroblastoma overexpressed (NOV), is an adipocytokine that has recently been suggested to be secreted selectively by hypothalamic arcuate nucleus kisspeptin (ARNKISS) neurons to protect bone density during lactation. Using RNAscope hybridization, we have examined the expression of
Shel‐Hwa Yeo   +5 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah   +8 more
wiley   +1 more source

Re: Nonmelanomatous Skin Cancer Following Cervical, Vaginal, and Vulvar Neoplasms:Etiologic Association [CORRESPONDENCE] [PDF]

open access: yes, 2017
Frisch, Morten   +4 more
core  

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