Results 241 to 250 of about 51,385 (333)

Integrated ERK‐PKA‐YAP/TAZ‐SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang   +13 more
wiley   +1 more source

Comparative efficacy, feasibility and acceptability of HPV DNA testing on first-void urine versus self-collected vaginal samples: a real-world study in a resource-limited setting. [PDF]

open access: yesBMJ Glob Health
Bose S   +11 more
europepmc   +1 more source

Safety and Efficacy of Pelvic Reinforcement Procedure for Preventing Postoperative Perineal Hernia After Robotic Abdominoperineal Resection: A Single‐Center, Retrospective Cohort Study

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 128-136, January 2026.
This study aimed to investigate the safety and efficacy of pelvic reinforcement procedure (PRP) in robotic abdominoperineal resection (Ro‐APR). PRP‐ had a significantly higher rate of imaged perineal hernia (PH) (39.2% vs. 6.7%, p = 0.005) and symptomatic PH (19.6% vs.
Yoshihiro Sakai   +8 more
wiley   +1 more source

Case Series of Nizon‐Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid–Triploid Mosaicism

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 205-214, January 2026.
ABSTRACT Nizon‐Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7‐year‐old female who presented with developmental delay, right‐leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin ...
Russell Stewart   +336 more
wiley   +1 more source

Innovative vaginal wash formulation with Chitosan nanoparticles targets microbial pathogens, ovarian cancer and inflammation. [PDF]

open access: yesSci Rep
Al-Rajhi AMH   +9 more
europepmc   +1 more source

Flow Cytometry: Advances, Challenges and Trends

open access: yesBioEssays, Volume 48, Issue 1, January 2026.
Recent advances in flow cytometry span hardware, data processing, and AI‐driven analytics. Emerging modalitiesincluding spectral, imaging, mass, and nano/EV cytometryenable higher‐parameter and small‐particle detection. Integrated machine learning drives a shift from manual gating toward automated multi‐omics workflows.
J. Paul Robinson   +2 more
wiley   +1 more source

A Retrospective Study on the Clinicopathological Characteristics and Prognostic Analysis of Gynecologic Neuroendocrine Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Gynecologic neuroendocrine carcinomas (NECs) are rare, highly aggressive malignancies with early metastatic potential and limited evidence to guide optimal management across different primary sites. Aims To characterize the clinicopathological features, treatment patterns, survival outcomes, and prognostic factors of gynecologic ...
Yedan Ren   +3 more
wiley   +1 more source

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