Results 41 to 50 of about 8,495 (212)

Surgery for Older Cancer Patients: Cross‐Organ Review and Good Practice Statement by the Japanese Geriatric Oncology Guideline Committee

Annals of Gastroenterological Surgery, EarlyView.
We conducted a cross‐organ review of surgical outcomes in older cancer patients based on literature cited in Japanese clinical guidelines. This study summarizes postoperative complication rates and survival outcomes across five major cancer types. The findings aim to support the development of geriatric oncology surgical guidelines tailored to Japan's ...
Chie Tanaka, Takashi Ofuchi, Kiichiro Ninomiya, Daisuke Inoue, Ken Sugimoto, Keiko Murofushi, Toru Okuyama, Shigeaki Watanuki, Chiyo Imamura, Daisuke Sakai, Naomi Sakurai, Kiyotaka Watanabe, Kazuo Tamura, Toshiaki Saeki, Hiroshi Ishiguro   +14 more
wiley   +1 more source

HE4 in the differential diagnosis of ovarian masses [PDF]

, 2015
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela, ANGELONI, Antonio, Flavia Longo, MANGANARO, Lucia, PORPORA, Maria Grazia, Teresa Granato   +5 more
core   +1 more source

Truncating Variants in RREB1 Cause a Novel RASopathy Syndrome of Congenital Heart Disease, Genitourinary Malformations, and Developmental Delay

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The interstitial 6p microdeletion syndrome is characterized by dysmorphic facies and structural heart, kidney, brain, and musculoskeletal differences. RREB1 haploinsufficiency and consequent abnormal RAS‐MAPK pathway signaling have been proposed as a driver of the disease phenotype; however, apart from a single case report, the phenotype of ...
Alanna Strong, Caoimhe McKenna, Karen Stals, Antonio Vitobello, Mathilde Renaud, Claudine Rieubland, Michel Guipponi, Christophe Philippe, Paul Vrana, Alisa Gaskell, A. Micheil Innes, Alyssa L. Rippert, Rebecca Ahrens‐Nicklas, Elizabeth Bhoj, Kiersten Keller, Bimal P. Chaudhari, Brandon S. Stone   +16 more
wiley   +1 more source

Primary vaginal Ewing’s sarcoma/primitive neuroectodermal tumour: diagnostic and treatment challenges [PDF]

, 2014
Extra osseous Ewing’s sarcoma/primitive neuroectodermal tumour (PNET) of the genital tract of women is scarcely\ud described in the literature and involvement of the vagina is even rarer with a very few cases reported so far.
Debdatta Basu, K. Gunaseelan, K.S Reddy, Pranabandhu Das, Ramesh Ananthakrishnan   +4 more
core   +1 more source

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, EarlyView.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Imaging for juvenile angiofibroma [PDF]

, 2002
Juvenile angiofibroma presents characteristic imaging signs, many of which allow diagnosis and accurate estimation of extent without recourse to the dangers of biopsy.
Howard, D, Lloyd, G, Lund, VJ, Savy, L
core   +1 more source

Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

Chemistry &Biodiversity, EarlyView.
ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad, El‐Mahdi Ourhzif, Salha Hamri, Hafid Abderrafia, Mostafa Khouili, Maria Dolors Pujol   +5 more
wiley   +1 more source

Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment [PDF]

, 2012
Treatment for CIN is usually undertaken in an outpatient colposcopy clinic to remove the pre-cancerous cells from the cervix. It commonly involves lifting the cells off the cervix with electrically heated wire (diathermy) or laser, or destroying the ...
AI-Kurdi, Anthony, Connell, Crompton, Cruickshank, Deeks, DerSimonian, Diakomanolis, Duncan, Frega, Higgins, Howells, Huskisson, Johnson, Johnston, Jordan, Lee, Lipscomb, Lowles, Martin-Hirsch, Melzack, Mikhail, Moore, Peto, Rogstad, Sammarco, Sant, Sarkar, Sharp, Spielberger, Winters, Zigmond   +31 more
core   +1 more source