Results 71 to 80 of about 51,385 (333)

Vulvar and Vaginal Melanomas—The Darker Shades of Gynecological Cancers

Biomedicines, 2021
Melanomas of the skin are poorly circumscribed lesions, very frequently asymptomatic but unfortunately with a continuous growing incidence. In this landscape, one can distinguish melanomas originating in the mucous membranes and located in areas not ...
Elena-Codruța Dobrică, Cristina Vâjâitu, Carmen Elena Condrat, Dragoș Crețoiu, Ileana Popa, Bogdan Severus Gaspar, Nicolae Suciu, Sanda Maria Crețoiu, Valentin Nicolae Varlas   +8 more
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Primary Vaginal Mucinous Adenocarcinoma of Intestinal Type—Clinical, Radiological and Morphological Aspects

Medicina
Background and Objectives: Neoplasms of the vagina are rare and account for 1–2% of all tumors of the female reproductive system. Primary neoplasms of the vagina are most often carcinomas originating from squamous or glandular epithelium.
Tatyana Betova, Radoslav Trifonov, Savelina Popovska, Angel Yordanov, Konstantina Karakadieva, Zhivka Dancheva, Stoyan Kostov   +6 more
doaj   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Background and precancerous processes in the vulva and vagina: etiology, pathogenesis, diagnosis and treatment

Акушерство, гинекология и репродукция, 2019
Leukoplakia, kraurosis and pointed condylomas (papillomas) of the vulva represent the group of background benign vulvar diseases. Vulvar and vaginal intraepithelial neoplasms are classified as premalignant conditions.
A. G. Solopova, E. V. Tselovalnikova, V. S. Moskvichyova, T. A. Blbulyan, A. S. Shkoda, A. D. Makatsariya   +5 more
doaj   +1 more source

HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis [PDF]

, 2009
Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous ...
A Ouban, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Cubilla, AL Seixas, AS Masih, AS Narayana, B Kleter, C Dianzani, C Missero, Catherine Corbishley, CB Bunker, CL Haycox, Daniel M Berney, David M Prowse, DE Johnson, DM Prowse, E Ferreux, EF Velazquez, Elena Ktori, Elzbieta Stankiewicz, FT Kraus, GD Higgins, IB Roninson, Jack Cuzick, JC Noel, JR Nevins, KH Cuesta, KW Chan, KY Lam, KY Lam, L Gregoire, Laurence Ambroisine, LC Cubilla, LH Sobin, LL Villa, LV Ackerman, M Gualco, M Senba, M Serrano, M Wong, MA Rubin, MR Cupp, MT Kiyabu, Nicholas Watkin, PA Adegboyega, PA Hall, PH McKee, S Pilotti, Sakunthala C Kudahetti, SL Harris, T Sano, TH Cheung, VA Tron, VA Varma, Xiaoxi Zhang, Y Koyamatsu   +58 more
core   +1 more source

Systematic Review and Meta‐Analysis of Short‐ and Long‐Term Outcomes Following Natural Orifice Specimen Extraction for Colon Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Natural orifice specimen extraction (NOSE) in colon cancer surgery raises concerns about intra‐abdominal infection, peritoneal seeding, and local recurrence due to possible tumor cell implantation. This systematic review and meta‐analysis compares complete intracorporeal resection with NOSE versus conventional laparoscopic colon ...
Daichi Kitaguchi, Antonello Forgione, Mariano Giménez, Tatsuya Oda, Jacques Marescaux   +4 more
wiley   +1 more source

Surgical mistake causing an high recto-vaginal fistula. A case report with combined surgical and endoscopic approach: therapeutic considerations [PDF]

, 2013
BACKGROUND: Rectovaginal fistulas (RVFs) have multiple causes, size and location on which the surgical treatment depends. DESCRIPTION: The Authors consider different approaches to RVFs and describe a clinical case of recurrent high RVF. CONCLUSIONS: Most
AMATO, BRUNO, DANZI, MICHELE, Fabozzi Massimiliano, Grimaldi Luciano, Pannullo Mario, Reggio Stefano   +5 more
core   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell turnours [PDF]

, 2007
Background: Sertoli-Leyclig cell tumours of the ovary account for only 0.2% of malignant ovarian tumours. Two-thirds of all patients become apparent due to the tumour's hormone production. Methods: A 41-year-old patient (gravida 4, para 4) presented with
Campisi P, Ching B, Clinton CW, Dhont M, Emons G, Gershenson DM, O'Hern TM, Prinz RA, Schwartz PE, Tampakoudis P, Young RH, Young RH, Zaloudek C   +12 more
core   +2 more sources