Results 31 to 40 of about 983,982 (207)

‘Distraction Vaginogenesis’: Preliminary Results Using a Novel Method for Vaginal Canal Expansion in Rats

Bioengineering, 2023
Vaginal atresia is seen in genetic disorders such as Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome, which can cause significant sexual dysfunction.
Hannah Meyer, Lexus Trosclair, Sean D. Clayton, Collyn O’Quin, Zachary Connelly, Ross Rieger, Nhi Dao, Ahmed Alhaque, Andrew Minagar, Luke A. White, Giovanni Solitro, Mila Shah-Bruce, Valerie L. Welch, Stephanie Villalba, Jonathan Steven Alexander, Donald Sorrells   +15 more
doaj   +1 more source

Small intestinal submucosa promotes angiogenesis via the Hippo pathway to improve vaginal repair

Biomolecules & Biomedicine, 2023
Vaginal reconstruction has incorporated the use of gastrointestinal segments for decades, but the technique is inevitably associated with complications. Tissue-engineering techniques, however, have brought great hope for vaginal reconstruction.
Yanlai Xiao, Yanpeng Tian, Jingkun Zhang, Qian Li, Wenxin Shi, Xianghua Huang   +5 more
doaj   +1 more source

Management of High Urogenital Sinus in Adults: A Scoping Review

Medicina
Background and Objectives: Persistent urogenital sinus (PUGS) is a rare congenital anomaly resulting from disruptions in urogenital development during embryogenesis.
Muhammed A. Moukhtar Hammad, Nardeen Magdy Samaan, Gamal Ghoniem   +2 more
doaj   +1 more source

Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency

Advanced Science, EarlyView.
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen, Zong Chen, Chenzhi Lai, Yingying Yue, Tian He, Hao Gong, Jing Shi, Xiaoshuang Guo, Yu Wang, Guodong Song, Xiaolei Jin   +10 more
wiley   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Are women who work in bars, guesthouses and similar facilities a suitable study population for vaginal microbicide trials in Africa? [PDF]

, 2010
BACKGROUND: A feasibility study was conducted to investigate whether an occupational at-risk cohort of women in Mwanza, Tanzania are a suitable study population for future phase III vaginal microbicide trials.
Suzanna C. Francis, Stella Kasindi, Watson-Jones Deborah, Shagi, Charles, Claire Cook, Francis, Suzanna C, Watson-Jones, Deborah, Tobias Chirwa, Cook, Claire, Richard J. Hayes, Suzanna C Francis, Microbicides Development Programme, Louise Knight, Vallely Andrew, Celia Barberousse, Hayes, Richard J, Deborah Watson-Jones, Francis Suzanna C., Knight, Louise, Ross, David, Ian R Hambleton, Changalucha John, Everett Dean, Everett, Dean, Hambleton Ian R., Vallely, Andrew, Charles Shagi, Cook Claire, Changalucha, John, Shagi Charles, Hambleton, Ian R, Chirwa, Tobias, John Changalucha, Barberousse Celia, Kasindi Stella, Knight Louise, Dean Everett, Richard J Hayes, null null, Kasindi, Stella, Barberousse, Celia, Ian R. Hambleton, Ross David, Chirwa Tobias, Andrew Vallely, David Ross, Hayes Richard J.   +46 more
core   +1 more source

Simultaneous bladder and vaginal reconstruction using ileum in complicated vesicovaginal fistula

Indian Journal of Urology, 2008
Objectives: To discuss the outcome of surgical repair in complicated vesicovaginal fistula with simultaneous bladder and vaginal reconstruction using ileum. Materials and Methods: Four female patients in the age group of 12-30 years are included.
Sujata K Patwardhan, Ajit Sawant, Mohammad Ismail, M Nagabhushana, Radheshyam R Varma   +4 more
doaj   +1 more source

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

Advanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen, Weiyi Wang, Yang Wang, Yiqiang Wu, Xiaohong Liu, Wei Zhang, Juanjuan Ou   +6 more
wiley   +1 more source

Resilient customized hollow vaginal stent for the treatment of vaginal agenesis in mayer–Rokitansky–Kuster–hauser syndrome

Nigerian Journal of Surgery, 2020
Vaginal agenesis is a common congenital anomaly in females and is most commonly associated with Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome. These patients can be treated with both surgical and nonsurgical procedures.
Manu Rathee, Savita Rani Singhal, Sanju Malik, Gunjan Gupta   +3 more
doaj   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source