Results 131 to 140 of about 30,150 (245)

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2592-2612, May 2026.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu   +8 more
wiley   +1 more source

Paternal sleep deprivation and cardiac dysfunction in offspring: A perspective of myocardial hypertrophy

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2518-2527, 1 May 2026.
Abstract The objective of this work is to assess the effects and potential process of paternal acute sleep deprivation on cardiac function in their offspring. Male and female C57BL/6N mice aged 8–9 weeks (n = 4–5 mice/group) were used. Male mice were selected to construct an acute sleep deprivation model using the modified multiple platform method ...
Yingying Zhang   +12 more
wiley   +1 more source

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high‐grade serous ovarian carcinoma

open access: yesInternational Journal of Cancer, Volume 158, Issue 8, Page 2043-2050, 15 April 2026.
What's New? High‐grade serous ovarian carcinoma is often diagnosed at advanced stages due to non‐specific symptoms and the lack of reliable screening methods. This proof‐of‐concept study introduces a novel TP53 mutation panel using unique molecular identifier‐based next‐generation sequencing for sensitive detection of high‐grade serous ovarian ...
Amanda Olsson Widjaja   +11 more
wiley   +1 more source

Detection of Abnormal Cervical Cytology by Pap Smears

open access: yesGomal Journal of Medical Sciences, 2004
Background: Cervical intra-epithelial neoplasia and cervical cancer remain important health problems for women worldwide. Cervical cytology by Papanicolaou stained smears is an effective means of screening for cervical pre-malignant and malignant ...
Sania Tanveer Khattak   +4 more
doaj  

Modelling the impact of referral guideline changes for mild dyskaryosis on colposcopy services in England [PDF]

open access: yes
Objectives: This model examines the effects of changing referral strategies within the established structure of NHS cervical screening driven colposcopy practice. It considers the effects of the new strategy on colposcopy workload, patient waiting times,
Brennan, A.   +3 more
core  

Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Yajing Weng   +12 more
wiley   +1 more source

Spectrum of infections in cervico-vaginal pap smears

open access: yesJournal of Clinical and Biomedical Sciences, 2014
Aparna Narasimha   +4 more
doaj   +1 more source

Penentuan Siklus Estrus pada Kancil (Tragulus javanicus) Berdasarkan Perubahan Sitologi Vagina

open access: yesJurnal Veteriner, 2010
The aim of this study was to determine the estrus cycle and the length of estrus in Tragulus javanicuson the basis of its vaginal cytology. Vaginal swabs were collected daily at 7 am for two months. Smears ofthe swab were then prepared on glass slide and
Najamudin -   +5 more
doaj  

DETECTION OF COLONIZATION OF PREGNANT WOMEN WITH STREPTOCOCCUS AGALACTIAE IN THE SEVERNOPRIMORSKA REGION

open access: yesZdravniški Vestnik, 2001
Background. Streptococcus agalactiae (GBS) is a leading cause of neonatal sepsis and meningitis. Newborns are colonized with GBS at the time of delivery.
Jerneja Fišer   +3 more
doaj  

Somatic mutations in cervicovaginal samples: assessing their role in ovarian cancer detection and prognosis. [PDF]

open access: yesTransl Oncol
Pelegrina B   +20 more
europepmc   +1 more source

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