Results 41 to 50 of about 18,438 (243)

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

Animal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang, Yan Zan, Tiantian Ma, Xiaoquan Huang, Junwei Li, Liangjun Xia, Yuping Sa, Youbing Xia   +7 more
wiley   +1 more source

Probiotic supplementation during pregnancy for vaginal microbiota improvement and pathogen clearance: A systematic review and meta-analysis. [PDF]

Acta Obstet Gynecol Scand
Probiotic supplementation during pregnancy shows a modest, non‐robust increase in Group B Streptococcus decolonization, with no consistent benefit for bacterial vaginosis or vulvovaginal candidiasis. Probiotics may serve as a non‐antibiotic adjunct, but standardized regimens and ecological diagnostic frameworks are required.
Liu Z, Huang R, Sun T, Zhu L.
europepmc   +2 more sources

Colpocitologia oncótica na gestacão. [PDF]

, 1993
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Tocoginecologia, Curso de Medicina, Florianópolis ...
Schutzler, Karin Grunsch
core  

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

High acceptability of point‐of‐care HIV testing at the colposcopy outpatient clinic in hospitals in the Netherlands

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 155-162, April 2025.
Abstract Objective Cervical cancer and its precursor are labeled as HIV indicator conditions, justifying the recommendation of HIV testing for all patients. This study aimed to assess the acceptance and patients' and gynecologists' perceptions on HIV testing in patients with cervical dysplasia at the colposcopy outpatient clinic in hospitals in the ...
R. L. O. van de Laar, C. C. E. Jordans, A. Salmaan, W. Hofhuis, S. A. H. M. van den Tillaart, I. A. M. van der Avoort, P. J. Timmers, H. J. van Beekhuizen, H. C. van Doorn, C. Rokx   +9 more
wiley   +1 more source

Fluorescence micrographs and Gram stain images of vaginal fluid smears.

, 2013
Vaginal fluid smears from two representative study participants are shown. 4+ curved rods were documented by Gram stain (A & C) for both participants who had BV (Nugent score 10).
Sujatha Srinivasan (158064), Jeanne M. Marrazzo (158103), Frederick A. Matsen (156498), Tina L. Fiedler (158079), Congzhou Liu (132136), Noah G. Hoffman (158068), Martin T. Morgan (158071), Kathy J. Agnew (365568), David N. Fredricks (118182)   +8 more
core   +1 more source

Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term‐births in northern Uganda: A cross sectional analytical study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare, James K. Tumwine, Jolly Nankunda, Anna Hjelmstedt, Wibke Jonas, Grace Ndeezi, Nicola Orsini, Claudia Hanson   +7 more
wiley   +1 more source

Perinatal outcomes in normotensive versus hypertensive HELLP syndrome

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare maternal and neonatal outcomes between women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome with and without associated hypertension. Methods This was a retrospective cohort study at a tertiary university‐affiliated medical center including all singleton HELLP cases >24 weeks gestation (January ...
Matan Anteby, Keren‐Or Wertheimer, Omri Dominsky, Liran Hiersch, Yariv Yogev   +4 more
wiley   +1 more source

A Comparison of the Use of Papanicolaou-stained Cervical Cytological Smears with Gram-stained Vaginal Smears for the Diagnosis of Bacterial Vaginosis in Early Pregnancy

, 1999
Our objective is to compare the efficacy of using Papanicolaou (PAP)-stained cervical cytology smears with a standardized method of interpreting Gram-stained vaginal smears for the diagnosis of bacterial vaginosis (BV) in pregnancy. High vaginal smears
Ronald F Lamont, Vikash Modi, David Taylor-Robinson, Elizabeth A Hudson, Cathy A Ison Frcpath, Phillip E Hay, D John Morgan   +6 more
core   +1 more source